Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5785221 | 0.82 | KMT2A (0.47) | KMT2ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL19707384 | 0.77 | KMT2A (0.49) | KMT2ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL19707381 | 0.72 | ADRA2C (0.55) | KMT2ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL19707293 | 0.71 | FPR2 (0.51) | KMT2AMEN1S1PR3LMNAGAA | |
| SCHEMBL27860227 | 0.71 | CNR1 (0.41) | KMT2ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL15137379 | 0.71 | ALDH1A1 (0.62) | KMT2AMEN1S1PR3LMNAGAA | |
| SCHEMBL5786454 | 0.71 | ALDH1A1 (0.62) | KMT2AMEN1S1PR3LMNAGAA | |
| SCHEMBL15137210 | 0.71 | ALDH1A1 (0.62) | KMT2AMEN1S1PR3LMNAGAA | |
| SCHEMBL28780674 | 0.70 | LMNA (0.56) | SLC6A2SLC6A4SLC6A3LMNATRPA1 | |
| SCHEMBL28359204 | 0.70 | KMT2A (0.77) | KMT2AMEN1S1PR3LMNAFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214505-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2017-12-14 | — | — | WO | disclosed |