Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714133 | 1.00 | ITGB3 (0.33) | ITGB3ITGB1ITGAVITGA5CNR2 | |
| Carbamic Acid SCHEMBL27983163 | 0.96 | ITGB3 (0.35) | ITGB3ITGB1ITGAVITGA5CNR2 | |
| SCHEMBL24218813 | 0.86 | ENPEP (0.35) | CNR2CNR1SMN1; SMN2HPGDSENPEP | |
| SCHEMBL21917418 | 0.84 | EPHX1 (0.31) | EPHX1CA1CA2 | |
| SCHEMBL21843952 | 0.84 | EPHX1 (0.31) | EPHX1CA1CA2 | |
| SCHEMBL21034776 | 0.84 | EPHX1 (0.31) | EPHX1CA1CA2 | |
| SCHEMBL16852138 | 0.82 | SMN1; SMN2 (0.37) | CNR2CNR1SMN1; SMN2EPHX1CA1 | |
| SCHEMBL30700134 | 0.82 | ALDH1A1 (0.41) | CA1CA2ENPEPHTT | |
| SCHEMBL14012364 | 0.81 | HPGDS (0.31) | ITGB3ITGB1ITGAVITGA5HPGDS | |
| SCHEMBL26439512 | 0.80 | HTT (0.35) | SMN1; SMN2CA1HTTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355708-A1 | POTASSIUM CHANNEL MODULATORS | CADENT THERAPEUTICS, INC. | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355708-A1 | POTASSIUM CHANNEL MODULATORS | KCNJ11, KCNJ2, KCNJ1 | ITGB3 3611/4885ITGB1 2339/4885ITGAV 2262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.