Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3149936 | 0.93 | KMT2A (0.63) | PARP10KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL9189720 | 0.91 | PARP10 (0.67) | PARP10KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL5710451 | 0.91 | PARP10 (0.67) | PARP10KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL26375073 | 0.89 | PARP10 (0.65) | PARP10KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL26039015 | 0.89 | PARP10 (0.70) | PARP10KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL4425652 | 0.89 | PARP10 (0.65) | PARP10KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL197094 | 0.89 | KMT2A (0.63) | PARP10KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL26038599 | 0.87 | PARP10 (0.67) | PARP10KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL2462824 | 0.87 | PARP10 (0.61) | PARP10KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL2638440 | 0.87 | PARP10 (0.67) | PARP10KMT2AMEN1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743777-B1 | TRISPHENYL ACYL DERIVATIVES OF THE ECHINOCANDIN CLASS; CANDIDA ALBICANS; ANTIFUNGAL AND ANTIPARASITIC; CYCLIC HEXAPEPTIDES HAVING UNIQUE SIDE CHAIN ACYL GROUP | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |
| US-6743777-B1 | TRISPHENYL ACYL DERIVATIVES OF THE ECHINOCANDIN CLASS; CANDIDA ALBICANS; ANTIFUNGAL AND ANTIPARASITIC; CYCLIC HEXAPEPTIDES HAVING UNIQUE SIDE CHAIN ACYL GROUP | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |