Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654049 | 0.92 | TDP1 (0.72) | TDP1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL28173861 | 0.83 | TDP1 (0.54) | TDP1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL11349579 | 0.82 | TDP1 (0.55) | TDP1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL28896841 | 0.77 | TDP1 (1.00) | TDP1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL3889771 | 0.76 | MAPT (0.48) | TDP1MAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL3895279 | 0.76 | MAPT (0.48) | TDP1MAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL7716422 | 0.76 | L3MBTL1 (0.71) | TDP1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL19712963 | 0.76 | TDP1 (0.47) | TDP1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL3690292 | 0.75 | TDP1 (0.50) | TDP1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9049960 | 0.75 | MAPT (0.64) | TDP1MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329244-B2 | Moisture-stable holographic media | COVESTRO DEUTSCHLAND AG (DE) | 2019-06-25 | — | — | US | disclosed |
| US-20170362165-A1 | MOISTURE-STABLE HOLOGRAPHIC MEDIA | COVESTRO DEUTSCHLAND AG (DE) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329244-B2 | Moisture-stable holographic media | NEFM, MDM4, BHMT2 | TDP1 1478/4885MAPT 343/4885ALDH1A1 3155/4885 |
| US-20170362165-A1 | MOISTURE-STABLE HOLOGRAPHIC MEDIA | NEFM, MDM4, BHMT2 | TDP1 1478/4885MAPT 343/4885ALDH1A1 3155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.