Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974686 | 0.95 | KDM4E (0.52) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL19717844 | 0.93 | MEN1 (0.65) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL15655618 | 0.93 | ALDH1A1 (0.56) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL13109053 | 0.83 | KDM4E (0.79) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL973615 | 0.83 | KDM4E (0.79) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL10879664 | 0.81 | ALDH1A1 (0.49) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL3765406 | 0.81 | KDM4E (0.81) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL28878425 | 0.79 | KDM4E (0.72) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL9136787 | 0.79 | KDM4E (0.72) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL29010714 | 0.78 | KDM4E (0.63) | KDM4EKMT2AMEN1RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875283-B2 | A stent coated with hydrophobic polymer having water-labile bonds and strength to withstand forces of the vascular systems and also biodegrades on its surface rather than bulk erosion; mechanical properties; drug delivery; a polyester,-anhydride or -amide having the monomer, trimellitylimidotyrosine | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-01-25 | — | — | US | disclosed |
| US-20050232971-A1 | Biodegradable polymers for use with implantable medical devices | HOSSAINY SYED F | 2005-10-20 | — | — | US | disclosed |