Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19719710 | 0.79 | NAPRT (0.47) | ADRA2AADRA2BADRA2CGAAMEN1 | |
| SCHEMBL383413 | 0.76 | NNMT (0.70) | NNMTHCAR3KDM4E | |
| Hydrazine SCHEMBL628678 | 0.74 | NNMT (0.68) | NNMTHCAR3KDM4E | |
| SCHEMBL8722229 | 0.72 | NNMT (0.50) | NNMTHCAR3KDM4EGAAMAPT | |
| SCHEMBL29505896 | 0.72 | HCAR3 (0.67) | HCAR3 | |
| SCHEMBL16382028 | 0.72 | HCAR3 (0.43) | NNMTHCAR3 | |
| SCHEMBL158601 | 0.72 | HCAR3 (0.67) | HCAR3 | |
| Acetone SCHEMBL17558521 | 0.71 | NNMT (0.69) | NNMTHCAR3KDM4E | |
| Hydrochloric Acid SCHEMBL5789616 | 0.70 | HCAR3 (0.65) | HCAR3 | |
| SCHEMBL217496 | 0.70 | NNMT (0.49) | NNMTHCAR3KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188938-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE | AKEBIA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |