Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7788094 | 0.78 | PLCG1 (0.33) | PLCG1KDM4CKDM4EMEN1ALDH1A1 | |
| SCHEMBL12498325 | 0.78 | EGLN2 (0.36) | EGLN2IDO1TDO2PLCG1ERBB2 | |
| SCHEMBL11041531 | 0.75 | KDM4E (0.36) | EGLN2IDO1TDO2ERBB2KDM4E | |
| SCHEMBL17416894 | 0.75 | MEN1 (0.39) | PLCG1ERBB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL30527748 | 0.75 | MEN1 (0.39) | PLCG1ERBB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL4385911 | 0.75 | ALDH1A1 (0.36) | EGLN2PLCG1ERBB2ALDH1A1GAA | |
| SCHEMBL28432011 | 0.71 | EGLN2 (0.36) | EGLN2KDM4CKDM4EMEN1ALDH1A1 | |
| SCHEMBL30630762 | 0.71 | PLCG1 (0.36) | EGLN2IDO1PLCG1ALOX5APFEN1 | |
| SCHEMBL17416877 | 0.71 | ALDH1A1 (0.42) | PLCG1KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL16238340 | 0.71 | CCR1 (0.41) | IDO1PLCG1KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668021-B1 | NOVEL THIOXYLOSE COMPOUNDS, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USE THEREOF IN THERAPEUTICS | FOURNIER LAB SA (FR) | 2011-06-22 | — | — | EP | disclosed |