Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19798237 | 0.78 | GSK3A (0.33) | PLCG1KDM4CCYP11B1 | |
| SCHEMBL4385911 | 0.78 | ALDH1A1 (0.36) | PLCG1ALDH1A1MAPTGAALMNA | |
| SCHEMBL17416894 | 0.78 | MEN1 (0.39) | PLCG1ALDH1A1MAPTCACNA1BAPBA1 | |
| SCHEMBL1972185 | 0.78 | EGLN2 (0.34) | PLCG1ALDH1A1MAPTCACNA1BAPBA1 | |
| SCHEMBL4385912 | 0.78 | PLCG1 (0.35) | PLCG1MAPTKDM4EKDM4CMAPK1 | |
| SCHEMBL30527748 | 0.78 | MEN1 (0.39) | PLCG1ALDH1A1MAPTCACNA1BAPBA1 | |
| SCHEMBL19774234 | 0.74 | NOS3 (0.35) | PLCG1ALDH1A1KDM4ECYP11B1PKM | |
| SCHEMBL16238340 | 0.74 | CCR1 (0.41) | PLCG1ALDH1A1MAPTCACNA1BAPBA1 | |
| SCHEMBL17416877 | 0.74 | ALDH1A1 (0.42) | PLCG1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL304561 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968189-B1 | PROCESS FOR THE PREPARATION OF NICOTINIC ACIDS | ABBOTT LAB (US) | 2001-11-07 | — | — | EP | disclosed |
| EP-0968189-A1 | PROCESS FOR THE PREPARATION OF NICOTINIC ACIDS | Abbott Laboratories (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998039298-A1 | PROCESS FOR THE PREPARATION OF NICOTINIC ACIDS | ABBOTT LABORATORIES (US) | 1998-09-11 | — | — | WO | disclosed |
| US-5739342-A | Process for the preparation of nicotinic acids | ABBOTT LABORATORIES (US) | 1998-04-14 | — | — | US | disclosed |