Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783436 | 0.75 | GABRA5 (0.33) | — | |
| SCHEMBL19723177 | 0.75 | ALDH1A1 (0.34) | ALDH1A1TDP1 | |
| SCHEMBL2621558 | 0.73 | KDM5A (0.37) | ALDH1A1TDP1 | |
| SCHEMBL24267978 | 0.73 | ALDH1A1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL23029116 | 0.73 | — | — | |
| SCHEMBL20847874 | 0.72 | ALDH1A1 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL15185671 | 0.72 | BMPR1B (0.36) | ALDH1A1TDP1 | |
| SCHEMBL19723235 | 0.68 | PTGS2 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL23229049 | 0.66 | GSK3A (0.32) | — | |
| SCHEMBL13988839 | 0.66 | ADORA2A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560967-B1 | Heterocyclic carboxylic acid amides as PDK1 inihibitors | BOEHRINGER INGELHEIM INT (DE) | 2017-12-20 | — | — | EP | disclosed |