Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13416963 | 0.97 | TBXAS1 (0.46) | TBXAS1FAAHCNR1CNR2SLC6A5 | |
| SCHEMBL19723966 | 0.86 | TBXAS1 (0.45) | TBXAS1FAAHCNR1CNR2SLC6A5 | |
| SCHEMBL13416478 | 0.80 | FAAH (0.41) | TBXAS1FAAHCNR1CNR2SLC6A5 | |
| SCHEMBL12664939 | 0.78 | SLC6A5 (0.58) | TBXAS1FAAHCNR1CNR2SLC6A5 | |
| SCHEMBL19059597 | 0.77 | TBXAS1 (0.68) | TBXAS1CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL26870323 | 0.77 | TBXAS1 (0.68) | TBXAS1CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL18381218 | 0.76 | CYP3A4 (0.70) | TBXAS1CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL18381401 | 0.75 | TBXAS1 (0.65) | TBXAS1CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL19723979 | 0.74 | HRH3 (0.49) | TSHRLMNA | |
| Ingavirin SCHEMBL18381264 | 0.74 | CYP3A4 (0.70) | TBXAS1CYP3A4CYP2D6TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340261-B1 | AMYLIN DERIVATIVES | NOVO NORDISK AS (DK) | 2017-12-20 | — | — | EP | disclosed |