Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 10/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 8/20 | 0.48 |
| ▸ | HRH2 | P25021 | 3/20 | 0.48 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117873 | 0.79 | HRH3 (0.47) | HRH3HRH4MEN1ALDH1A1GLA | |
| SCHEMBL17119231 | 0.79 | HRH3 (0.47) | HRH3HRH4MEN1ALDH1A1GLA | |
| SCHEMBL14213359 | 0.78 | HRH4 (0.50) | HRH3HRH4CPB2HRH1HRH2 | |
| SCHEMBL13416963 | 0.78 | TBXAS1 (0.46) | LMNATSHR | |
| SCHEMBL12735917 | 0.76 | HRH4 (0.47) | HRH3HRH4CPB2HRH1HRH2 | |
| SCHEMBL17119227 | 0.75 | HRH3 (0.50) | HRH3HRH4CPB2MEN1ALDH1A1 | |
| SCHEMBL9751643 | 0.75 | HRH3 (0.50) | HRH3HRH4CPB2MEN1ALDH1A1 | |
| SCHEMBL29312929 | 0.75 | HRH4 (0.46) | HRH3HRH4CPB2HRH1HRH2 | |
| SCHEMBL19724232 | 0.74 | TBXAS1 (0.48) | LMNATSHR | |
| SCHEMBL15412861 | 0.73 | CPB2 (0.61) | HRH3HRH4CPB2SLC15A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340261-B1 | AMYLIN DERIVATIVES | NOVO NORDISK AS (DK) | 2017-12-20 | — | — | EP | disclosed |