SCHEMBL19725192

SCHEMBL19725192

CSc1ncc(C(=O)O)cc1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.43
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 4/20 0.39
HSD17B10 Q99714 2/20 0.39
ALOX15 P16050 1/20 0.39
LMNA P02545 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
RAB9A P51151 1/20 0.39
MGAM O43451 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
CYP2C19 P33261 1/20 0.38
PSMD14 O00487 1/20 0.37
P4HA1 P13674 2/20 0.37
P4HTM Q9NXG6 2/20 0.37
ASPH Q12797 1/20 0.37
KDM8 Q8N371 1/20 0.37
VNN1 O95497 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10297731 0.80 HCAR2 (0.44) HCAR2ALDH1A1KDM4EHSD17B10ALOX15
SCHEMBL19738292 0.79 EGLN1 (0.40) ALDH1A1KDM4EMAPK1KMT2AEGLN1
SCHEMBL24520499 0.79 ALDH1A1 (0.43) HCAR2ALDH1A1KDM4EHSD17B10ALOX15
SCHEMBL13563113 0.79 MEN1 (0.44) HCAR2ALDH1A1KDM4EHSD17B10ALOX15
SCHEMBL8342407 0.78 VNN1 (0.41) HCAR2ALDH1A1KDM4EHSD17B10ALOX15
SCHEMBL114191 0.76 HCAR2 (0.47) HCAR2ALDH1A1KDM4EHSD17B10ALOX15
SCHEMBL3374192 0.75 RAB9A (0.44) HCAR2ALDH1A1KDM4EHSD17B10ALOX15
SCHEMBL898595 0.75 HCAR2 (0.50) HCAR2ALDH1A1KDM4EHSD17B10ALOX15
SCHEMBL30721127 0.75 HCAR2 (0.50) HCAR2ALDH1A1KDM4EHSD17B10ALOX15
SCHEMBL30963643 0.75 XDH (0.46) ALDH1A1KDM4EHSD17B10HPGDPSMD14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651907-A1 DRUG CONJUGATES AND METHODS OF PREPARING AND USING THE SAME Adcentrx Therapeutics Inc. (US) 2025-11-26 EP disclosed
WO-2024155761-A1 DRUG CONJUGATES AND METHODS OF PREPARING AND USING THE SAME ADCENTRX THERAPEUTICS INC. (US) 2024-07-25 WO disclosed
EP-3257847-A1 FXR (NR1H4) MODULATING COMPOUNDS Gilead Sciences, Inc. (US) 2017-12-20 EP disclosed