SCHEMBL19725202

SCHEMBL19725202

Cc1nc(-c2cccc3c2oc2ccccc23)c2ccccc2n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.43
ADORA2A P29274 1/20 0.42
MAPT P10636 4/20 0.40
ATM Q13315 1/20 0.40
PIK3CD O00329 1/20 0.40
PIK3CB P42338 1/20 0.40
PRKDC P78527 1/20 0.40
KDM4E B2RXH2 6/20 0.40
ALDH1A1 P00352 4/20 0.40
HTT P42858 3/20 0.40
HPGD P15428 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
TSHR P16473 2/20 0.40
USP2 O75604 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KMT2A Q03164 4/20 0.39
LMNA P02545 3/20 0.39
MEN1 O00255 3/20 0.39
TP53 P04637 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17524694 0.84 ALDH1A1 (0.43) ADORA2AMAPTATMKDM4EALDH1A1
SCHEMBL14233141 0.83 KDM4E (0.46) ALOX5ADORA2AMAPTPIK3CDPIK3CB
SCHEMBL17232204 0.82 KMT2A (0.48) ALOX5MAPTATMPIK3CDPIK3CB
SCHEMBL22736266 0.81 ADORA2A (0.51) ALOX5ADORA2AMAPTPIK3CDPIK3CB
SCHEMBL19725226 0.81 LMNA (0.41) ALOX5MAPTATMKDM4EALDH1A1
SCHEMBL19655089 0.81 ALOX5 (0.44) ALOX5ADORA2AMAPTPIK3CDPIK3CB
SCHEMBL17805946 0.79 ALOX5 (0.48) ALOX5MAPTATMPIK3CDPIK3CB
SCHEMBL16542822 0.77 ADORA2A (0.50) ADORA2AKDM4EALDH1A1HTTHPGD
SCHEMBL29985983 0.77 ADORA2A (0.50) ADORA2AKDM4EALDH1A1HTTHPGD
SCHEMBL21679705 0.77 CYP1A2 (0.44) ALOX5ADORA2AMAPTATMPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-20230389421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-30 US disclosed
US-20230363276-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230217818-A1 ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THEREOF LG DISPLAY CO., LTD. (KR) 2023-07-06 US disclosed
US-20230192714-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
US-20220336747-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-10-20 US disclosed
US-20220140256-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-05 US disclosed
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed
US-20170365795-A1 ORGANIC COMPOUND FOR OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220336747-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP ALOX5 256/4885ADORA2A 3371/4885MAPT 898/4885
US-20220140256-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, INMT ALOX5 178/4885ADORA2A 887/4885MAPT 1282/4885
US-20230363276-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 ALOX5 634/4885ADORA2A 2339/4885MAPT 758/4885
US-20230217818-A1 ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THEREOF OCIAD2, OCIAD1, DRD1 ALOX5 1971/4885ADORA2A 2765/4885MAPT 1845/4885
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 ALOX5 145/4885ADORA2A 3169/4885MAPT 966/4885
US-20170365795-A1 ORGANIC COMPOUND FOR OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OXER1, OR10J3, OCIAD1 ALOX5 440/4885ADORA2A 4055/4885MAPT 2456/4885
US-20230192714-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 ALOX5 142/4885ADORA2A 2746/4885MAPT 1568/4885
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 ALOX5 486/4885ADORA2A 4406/4885MAPT 429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.