SCHEMBL1972679

SCHEMBL1972679

CC(C)(C)c1cc(S)ccc1S

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
ALOX15 P16050 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
MAPT P10636 1/20 0.35
ATP2A2 P16615 1/20 0.35
ATP2A3 Q93084 1/20 0.35
TYR P14679 2/20 0.33
NR1I2 O75469 1/20 0.33
LMNA P02545 1/20 0.33
CYP2C9 P11712 1/20 0.33
MIF P14174 1/20 0.33
HTT P42858 1/20 0.33
NFE2L2 Q16236 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CA2 P00918 3/20 0.32
CA1 P00915 1/20 0.32
GLRA3 O75311 1/20 0.31
GLRB P48167 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4988858 0.82 ALDH1A1 (0.36) ALDH1A1ALOX15SMN1; SMN2KDM4ECYP1A2
SCHEMBL15063240 0.78 CYP1A2 (0.35) ALDH1A1ALOX15SMN1; SMN2KDM4ECYP1A2
SCHEMBL29529119 0.78 ALDH1A1 (0.43) ALDH1A1ALOX15SMN1; SMN2KDM4ECYP1A2
SCHEMBL333952 0.78 ALDH1A1 (0.44) ALDH1A1ALOX15SMN1; SMN2KDM4ECYP1A2
SCHEMBL7086864 0.78 ALDH1A1 (0.43) ALDH1A1ALOX15SMN1; SMN2KDM4ECYP1A2
SCHEMBL4748292 0.76 ALDH1A1 (0.61) ALDH1A1ALOX15SMN1; SMN2KDM4ECYP1A2
SCHEMBL9329634 0.76 ALDH1A1 (0.61) ALDH1A1ALOX15SMN1; SMN2KDM4ECYP1A2
SCHEMBL22991378 0.74 KIF11 (0.31)
SCHEMBL22737598 0.74 ESR1 (0.39) ALDH1A1ALOX15MAPTTSHR
SCHEMBL10333726 0.73 CYP1A2 (0.35) ALDH1A1ALOX15SMN1; SMN2KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2334661-B1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS UBE INDUSTRIES (JP) 2017-08-30 EP disclosed
CN-102224147-B Process for preparing poly (pentafluorosulfanyl) aromatic compounds UBE INDUSTRIES 2015-03-18 CN disclosed
US-8653302-B2 Processes for preparing poly(pentafluorosulfanyl)aromatic compounds UBE INDUSTRIES, LTD. (JP) 2014-02-18 US disclosed
CN-103382173-A Processes for preparing poly(pentafluorosulfanyl)aromatic compounds UBE INDUSTRIES 2013-11-06 CN disclosed
CN-102224147-A Process for preparing poly (pentafluorosulfanyl) aromatic compounds UBE INDUSTRIES 2011-10-19 CN disclosed
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds UBE INDUSTRIES, LTD. (JP) 2011-07-07 US disclosed
EP-2334661-A1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS Ube Industries, Ltd. (JP) 2011-06-22 EP disclosed
WO-2010033930-A1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS IM&T RESEARCH, INC. (US) 2010-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds PFAS, PUF60, FES ALDH1A1 4300/4885ALOX15 4427/4885SMN1; SMN2 2212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.