SCHEMBL19729680

SCHEMBL19729680

N#Cc1ccc2c(c1)c1ccccc1n2-c1cc(-c2ccccc2)ccc1-c1cccc(-c2ccccc2)c1-n1c2ccccc2c2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.33
RORC P51449 5/20 0.32
PTGER4 P35408 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CHEK1 O14757 1/20 0.32
PRKDC P78527 1/20 0.32
PGR P06401 1/20 0.32
ALDH1A3 P47895 1/20 0.32
METAP2 P50579 1/20 0.32
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
CSNK1A1 P48729 1/20 0.31
CSNK1D P48730 1/20 0.31
GSK3B P49841 1/20 0.31
CSNK1G2 P78368 1/20 0.31
MAPK14 Q16539 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19737821 1.00 PDK2 (0.33) PDK2RORCPTGER4MEN1KMT2A
SCHEMBL19729674 0.94 ADRA2C (0.34) PDK2RORCPTGER4MEN1KMT2A
SCHEMBL19729747 0.94 ADRA2C (0.34) PDK2RORCPTGER4MEN1KMT2A
SCHEMBL19737772 0.92 RORC (0.33) PDK2RORCPTGER4MEN1KMT2A
SCHEMBL19729681 0.92 RORC (0.33) PDK2RORCPTGER4MEN1KMT2A
SCHEMBL19697266 0.92 CHEK1 (0.33) PDK2PTGER4CHEK1PRKDCPGR
SCHEMBL19729785 0.91 MEN1 (0.34) RORCPTGER4MEN1KMT2AMETAP2
SCHEMBL19729667 0.91 MEN1 (0.34) RORCPTGER4MEN1KMT2AMETAP2
SCHEMBL19729757 0.90 PRKDC (0.34) RORCPTGER4MEN1KMT2APRKDC
SCHEMBL19729727 0.90 MEN1 (0.38) RORCPTGER4MEN1KMT2AMETAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957862-B2 Condensed cyclic compound for organic light-emitting device, and organic light-emitting device including the compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-03-23 US disclosed
US-20170365796-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-12-21 US disclosed
US-20170365796-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170365796-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 PDK2 2179/4885RORC 1161/4885PTGER4 473/4885
US-10957862-B2 Condensed cyclic compound for organic light-emitting device, and organic light-emitting device including the compound CRY1, CRY2, OCIAD1 PDK2 2098/4885RORC 1214/4885PTGER4 690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.