SCHEMBL1972989

SCHEMBL1972989

CCS(=O)(=O)Nc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.67
LMNA P02545 2/20 0.67
NR3C2 P08235 1/20 0.67
HTT P42858 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
AR P10275 1/20 0.61
KEAP1 Q14145 2/20 0.60
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
PSIP1 O75475 1/20 0.53
IL1RN P18510 1/20 0.52
ERAP1 Q9NZ08 1/20 0.52
KIF11 P52732 1/20 0.52
MAPT P10636 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
KMT2A Q03164 2/20 0.48
CA12 O43570 1/20 0.48
CA9 Q16790 1/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30763364 0.98 HPGD (0.65) HPGDLMNANR3C2HTTSMN1; SMN2
Acetic Acid SCHEMBL27557152 0.92 HPGD (0.69) HPGDLMNANR3C2HTTSMN1; SMN2
SCHEMBL255294 0.85 KEAP1 (0.54) HPGDLMNANR3C2HTTSMN1; SMN2
SCHEMBL15672897 0.83 CA2 (0.56) HPGDLMNANR3C2HTTSMN1; SMN2
SCHEMBL6533144 0.83 CA1 (0.56) HPGDLMNANR3C2ARKEAP1
Hydrochloric Acid SCHEMBL31111910 0.83 KEAP1 (0.52) HPGDLMNANR3C2HTTSMN1; SMN2
SCHEMBL4650966 0.81 AR (0.66) HPGDLMNANR3C2ARKEAP1
SCHEMBL10443735 0.81 CA2 (0.54) HPGDLMNANR3C2HTTSMN1; SMN2
SCHEMBL251932 0.80 AR (0.60) HPGDLMNANR3C2ARKEAP1
SCHEMBL8594869 0.79 KEAP1 (0.52) HPGDLMNANR3C2HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119101213-A Preparation process of fiber flame retardant 绍兴市贝固纺织有限公司 2024-12-10 CN claimed
US-11279687-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. (US) 2022-03-22 US claimed
CN-107779446-B Immobilized lysine decarboxylase, preparation thereof, preparation method of 1, 5-pentanediamine and product 上海凯赛生物技术股份有限公司 2021-09-07 CN claimed
CN-107779445-B Immobilized lysine decarboxylase, preparation thereof, preparation method of 1, 5-pentanediamine and product 上海凯赛生物技术股份有限公司 2021-02-19 CN claimed
US-9169209-B2 Compounds and compositions for the inhibition of NAMPT FORMA TM, LLC (US) 2015-10-27 US claimed
US-20140275057-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT Valo Health, LLC 2014-09-18 US claimed
WO-2012150952-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT FORMA TM, LLC (US) 2012-11-08 WO claimed
EP-0333656-A1 Reactive dyes, process for their preparation and their use CIBA-GEIGY AG (CH) 1989-09-20 EP claimed
US-4093492-A HEAT SEALING PLATE BONN GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-06-06 US claimed
US-4030957-A HEAT SEALING PLATE BONN GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-06-21 US claimed
US-3950297-A HEAT-SEALING AGENTS PLATE BONN GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-04-13 US claimed
US-3948844-A HEAT SEALANTS PLATE BONN GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-04-06 US claimed
US-20260078091-A1 Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer AMGEN INC (US) 2026-03-19 US disclosed
CN-119101213-A Preparation process of fiber flame retardant 绍兴市贝固纺织有限公司 2024-12-10 CN disclosed
CN-119101213-A Preparation process of fiber flame retardant 绍兴市贝固纺织有限公司 2024-12-10 CN disclosed
CN-114805147-B Aniline sulfonic acid intermediate for dye and preparation method thereof 南京晓庄学院 2024-09-13 CN disclosed
EP-0131302-A2 Imidazolium salts, intermediates thereto and their use SCHERING AKTIENGESELLSCHAFT (DE) 1985-01-16 EP disclosed
EP-0073481-A2 Water-soluble azo compounds, process for their manufacture and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1983-03-09 EP disclosed
EP-0065211-A1 Azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1982-11-24 EP disclosed
EP-0051808-A2 Water-soluble monoazo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1982-05-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11279687-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNT, NQO1 HPGD 199/4885LMNA 419/4885NR3C2 1764/4885
US-20260078091-A1 Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer TP53, HIF1AN, MDM2 HPGD 1074/4885LMNA 738/4885NR3C2 3693/4885
US-20140275057-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT NAMPT, NNMT, NAPRT HPGD 341/4885LMNA 1255/4885NR3C2 2495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.