Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 3/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 5/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19730203 | 0.88 | TSHR (0.41) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL19738183 | 0.88 | THRB (0.43) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL14028722 | 0.88 | TSHR (0.54) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL19730228 | 0.86 | ALDH1A1 (0.46) | THRBTSHRALDH1A1CYP3A4AKR1B10 | |
| SCHEMBL19730216 | 0.86 | ALDH1A1 (0.46) | THRBTSHRALDH1A1CYP3A4AKR1B10 | |
| SCHEMBL19730206 | 0.84 | MET (0.44) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL19730225 | 0.84 | AKR1B1 (0.42) | THRBTSHRALDH1A1CYP3A4MET | |
| SCHEMBL19730235 | 0.84 | THRB (0.43) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL19730250 | 0.83 | THRB (0.40) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL19730241 | 0.83 | AKR1B10 (0.45) | THRBTSHRHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170364025-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE INCLUDING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CANON KABUSHIKI KAISHA (JP) | 2017-12-21 | — | — | US | disclosed |