Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121494 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRITGB1ITGA4 | |
| SCHEMBL5648495 | 0.80 | ITGB1 (0.48) | ALDH1A1CYP3A4TSHRITGB1ITGA4 | |
| SCHEMBL6340899 | 0.79 | MCL1 (0.43) | ALDH1A1CYP3A4ITGB1ITGA4OPRK1 | |
| SCHEMBL6907862 | 0.79 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TSHRHSD17B1HSD17B2 | |
| SCHEMBL6908896 | 0.78 | ALDH1A1 (0.63) | ALDH1A1CYP3A4TSHROPRM1OPRK1 | |
| SCHEMBL6903155 | 0.75 | LMNA (0.45) | ALDH1A1CYP3A4TSHRCYP1A2HSD17B1 | |
| SCHEMBL19731898 | 0.75 | MCL1 (0.56) | ALDH1A1CYP3A4TSHRBCL2L1MCL1 | |
| SCHEMBL9618596 | 0.75 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHROPRM1OPRK1 | |
| SCHEMBL9310893 | 0.74 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TSHRBCL2L1MCL1 | |
| SCHEMBL9304794 | 0.73 | ALDH1A1 (0.73) | ALDH1A1CYP3A4TSHROPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170360667-A1 | NEW COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | L'OREAL (FR) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360667-A1 | NEW COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | H1-0, CRY1, CCNA1 | ALDH1A1 736/4885CYP3A4 3459/4885TSHR 1299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.