SCHEMBL19731905

SCHEMBL19731905

C/C=C\c1c(C)oc2cccnc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
L3MBTL1 Q9Y468 4/20 0.44
ATM Q13315 2/20 0.44
HSP90AA1 P07900 2/20 0.37
NPC1 O15118 1/20 0.37
MAPK14 Q16539 1/20 0.33
LMNA P02545 2/20 0.33
CCR1 P32246 4/20 0.32
CCR8 P51685 4/20 0.32
HTT P42858 3/20 0.32
KDM4E B2RXH2 3/20 0.32
MAPT P10636 3/20 0.32
CCR5 P51681 3/20 0.32
GMNN O75496 1/20 0.32
TP53 P04637 1/20 0.32
MMP2 P08253 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MMP9 P14780 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22627490 0.83 L3MBTL1 (0.44) MEN1KMT2AL3MBTL1ATMHSP90AA1
SCHEMBL19731908 0.82 L3MBTL1 (0.41) MEN1KMT2AL3MBTL1ATMHSP90AA1
SCHEMBL1707915 0.73 HTT (0.46) MEN1KMT2AL3MBTL1ATMHSP90AA1
SCHEMBL25656661 0.72 KDM4E (0.40) MEN1KMT2AL3MBTL1HSP90AA1NPC1
SCHEMBL18685767 0.71 KDM4E (0.47) MEN1KMT2AL3MBTL1KDM4EMAPT
SCHEMBL19053803 0.70 L3MBTL1 (0.62) MEN1KMT2AL3MBTL1HSP90AA1NPC1
SCHEMBL20967565 0.70 MEN1 (0.34) MEN1KMT2AL3MBTL1ATMMAPK14
SCHEMBL19721397 0.70 MEN1 (0.34) MEN1KMT2AL3MBTL1ATMMAPK14
SCHEMBL6925972 0.70 KDM4E (0.48) MEN1KMT2AL3MBTL1ATMHSP90AA1
SCHEMBL15676205 0.69 L3MBTL1 (0.60) MEN1KMT2AL3MBTL1HSP90AA1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10968229-B2 Seven-membered ring compounds IDEMITSU KOSAN CO., LTD. (JP) 2021-04-06 US disclosed
US-20190119291-A1 SEVEN-MEMBERED RING COMPOUNDS IDEMITSU KOSAN CO., LTD. (JP) 2019-04-25 US disclosed
US-20170362241-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) IDEMITSU KOSAN CO., LTD. (JP) 2017-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190119291-A1 SEVEN-MEMBERED RING COMPOUNDS MCM7, XPO7, LUC7L2 MEN1 441/4885KMT2A 3830/4885L3MBTL1 4616/4885
US-10968229-B2 Seven-membered ring compounds MCM7, XPO7, LUC7L2 MEN1 441/4885KMT2A 3830/4885L3MBTL1 4616/4885
US-20170362241-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) OCIAD1, OCIAD2, DDT MEN1 3404/4885KMT2A 4080/4885L3MBTL1 1179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.