SCHEMBL19731908

SCHEMBL19731908

C=C/C=C\c1c(C)oc2cccnc12

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ATM Q13315 2/20 0.41
NPC1 O15118 1/20 0.34
HSP90AA1 P07900 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK14 Q16539 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
LMNA P02545 1/20 0.30
FTO Q9C0B1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22627490 0.85 L3MBTL1 (0.44) L3MBTL1MEN1KMT2AATMNPC1
SCHEMBL19731905 0.82 MEN1 (0.44) L3MBTL1MEN1KMT2AATMNPC1
SCHEMBL18830876 0.73 KDM4E (0.43) L3MBTL1MEN1KMT2AKDM4EALDH1A1
SCHEMBL21841136 0.73 L3MBTL1 (0.56) L3MBTL1MEN1KMT2ANPC1HSP90AA1
SCHEMBL22432413 0.72 ELANE (0.33)
SCHEMBL19413657 0.72 LMNA (0.51) L3MBTL1MEN1KMT2AHSP90AA1KDM4E
SCHEMBL24201041 0.71 L3MBTL1 (0.49) L3MBTL1NPC1HSP90AA1KDM4EALDH1A1
SCHEMBL17792923 0.71 L3MBTL1 (0.44) L3MBTL1NPC1HSP90AA1KDM4EALDH1A1
SCHEMBL23183282 0.70 L3MBTL1 (0.39) L3MBTL1MEN1KMT2AATMNPC1
SCHEMBL14511529 0.69 NFE2L2 (0.34) L3MBTL1MEN1KMT2AATMNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170362241-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) IDEMITSU KOSAN CO., LTD. (JP) 2017-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170362241-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) OCIAD1, OCIAD2, DDT L3MBTL1 1179/4885MEN1 3404/4885KMT2A 4080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.