Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | GUSB | P08236 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108247 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1LMNAHTTGUSB | |
| SCHEMBL7265815 | 0.87 | ALDH1A1 (0.83) | ALDH1A1L3MBTL1LMNAGUSBMAPT | |
| SCHEMBL9814256 | 0.86 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1LMNAHTTGUSB | |
| SCHEMBL3394058 | 0.85 | ALDH1A1 (0.71) | ALDH1A1L3MBTL1LMNAHTTGAA | |
| SCHEMBL29531249 | 0.85 | ALDH1A1 (0.71) | ALDH1A1L3MBTL1LMNAHTTGAA | |
| SCHEMBL19752716 | 0.85 | ALDH1A1 (0.71) | ALDH1A1L3MBTL1LMNAHTTGAA | |
| SCHEMBL9805503 | 0.85 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1LMNAHTTGUSB | |
| SCHEMBL9805495 | 0.85 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1LMNAHTTGUSB | |
| SCHEMBL19732962 | 0.85 | ALDH1A1 (0.55) | ALDH1A1GUSBGAASMN1; SMN2USP2 | |
| SCHEMBL14413498 | 0.85 | ALDH1A1 (0.55) | ALDH1A1GUSBGAASMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260446-A1 | ENANTIOSELECTIVE SYNTHESIS OF DIHYDROPYRIMIDINONES AND HEXAHYDROPYRIMIDINONES | Universitat de les Illes Balears (ES) | 2017-12-27 | — | — | EP | disclosed |