SCHEMBL3394058

SCHEMBL3394058

CCOC(=O)C1=C(C)NC(=O)NC1c1cccc([N+](=O)[O-])c1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.71
GAA P10253 3/20 0.71
SMN1; SMN2 Q16637 2/20 0.71
L3MBTL1 Q9Y468 1/20 0.71
CACNA1F O60840 4/20 0.71
CACNA1D Q01668 4/20 0.71
CACNA1S Q13698 4/20 0.71
CACNA1C Q13936 4/20 0.71
ADORA3 P0DMS8 1/20 0.71
KIF11 P52732 1/20 0.71
HTT P42858 1/20 0.70
PKM P14618 2/20 0.68
RXFP1 Q9HBX9 1/20 0.68
MEN1 O00255 4/20 0.67
KMT2A Q03164 4/20 0.67
HIF1A Q16665 3/20 0.66
MAPT P10636 3/20 0.66
CYP1A2 P05177 2/20 0.66
CYP3A4 P08684 2/20 0.66
CYP2C9 P11712 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29531249 1.00 ALDH1A1 (0.71) ALDH1A1GAASMN1; SMN2L3MBTL1CACNA1F
SCHEMBL19752716 1.00 ALDH1A1 (0.71) ALDH1A1GAASMN1; SMN2L3MBTL1CACNA1F
SCHEMBL7437010 0.88 ALDH1A1 (0.77) ALDH1A1L3MBTL1CACNA1FCACNA1DCACNA1S
SCHEMBL3396126 0.88 PDE1C (0.69) ALDH1A1GAASMN1; SMN2L3MBTL1CACNA1F
SCHEMBL5339709 0.86 CA12 (0.68) ALDH1A1GAAL3MBTL1ADORA3KIF11
SCHEMBL19752618 0.86 CA12 (0.68) ALDH1A1GAAL3MBTL1ADORA3KIF11
SCHEMBL28789247 0.86 MEN1 (0.62) GAASMN1; SMN2CACNA1FCACNA1DCACNA1S
SCHEMBL8108247 0.85 ALDH1A1 (0.63) ALDH1A1GAASMN1; SMN2L3MBTL1CACNA1F
SCHEMBL19732964 0.85 ALDH1A1 (0.63) ALDH1A1GAASMN1; SMN2L3MBTL1CACNA1F
SCHEMBL5340534 0.84 KIF11 (0.80) ALDH1A1GAASMN1; SMN2L3MBTL1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110437100-B Preparation method and application of novel ionic salicylaldehyde Schiff base zirconium complex 山西医科大学 2022-03-11 CN disclosed
WO-2010046780-A2 ANTI VIRAL COMPOUNDS INSTITUT PASTEUR KOREA (KR) 2010-04-29 WO disclosed
WO-2010046780-A2 ANTI VIRAL COMPOUNDS INSTITUT PASTEUR KOREA (KR) 2010-04-29 WO disclosed
WO-2007101213-A2 NOVEL 2-OXO-1,2,3,4-TETRAHYDROPYRIMIDINES, BICYCLIC PYRIMIDINE DIONES AND IMIDAZOLIDINE-2,4-DIONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS KALYPSYS, INC. (US) 2007-09-07 WO disclosed