SCHEMBL19733281

SCHEMBL19733281

CCC(Cc1ccc(N2CCOCC2)cc1)(Cc1cccc(C)c1)N(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.42
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 3/20 0.42
NPC1 O15118 1/20 0.41
GAA P10253 1/20 0.41
RAB9A P51151 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
AOC3 Q16853 2/20 0.40
PIK3CD O00329 1/20 0.39
PIK3CA P42336 1/20 0.39
PIK3CB P42338 1/20 0.39
PIK3CG P48736 1/20 0.39
AGXT P21549 1/20 0.39
TSHR P16473 1/20 0.38
LMNA P02545 2/20 0.38
ALOX12 P18054 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL466267 0.88 RAB9A (0.52) MAPTALDH1A1KDM4ENPC1GAA
SCHEMBL1577100 0.88 LMNA (0.46) MAPTALDH1A1KDM4ENPC1GAA
SCHEMBL28288263 0.85 RAB9A (0.43) MAPTALDH1A1KDM4ENPC1GAA
SCHEMBL27871187 0.84 AOC3 (0.41) MAPTALDH1A1KDM4ENPC1GAA
SCHEMBL1242129 0.82 RORC (0.41) MAPTALDH1A1KDM4ENPC1GAA
SCHEMBL18166511 0.82 MAPT (0.39) MAPTALDH1A1KDM4ENPC1GAA
Formamide SCHEMBL27646730 0.81 SMN1; SMN2 (0.44) MAPTALDH1A1KDM4ENPC1RAB9A
Urea SCHEMBL27646729 0.81 SMN1; SMN2 (0.46) MAPTL3MBTL1AOC3PIK3CBLMNA
SCHEMBL19733282 0.81 LMNA (0.36) MAPTALDH1A1KDM4ENPC1GAA
SCHEMBL29378498 0.80 RORC (0.41) MAPTALDH1A1KDM4ENPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3085661-B1 METHOD OF PRODUCING MICROFLUIDIC DEVICE JSR CORP (JP) 2017-12-27 EP disclosed