SCHEMBL19733282

SCHEMBL19733282

CCCc1ccccc1CC(CC)(Cc1ccc(N2CCOCC2)cc1)N(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
MAPT P10636 6/20 0.36
ALDH1A1 P00352 5/20 0.36
KDM4E B2RXH2 2/20 0.36
MEN1 O00255 2/20 0.36
HTT P42858 2/20 0.36
KMT2A Q03164 2/20 0.36
USP2 O75604 1/20 0.36
TP53 P04637 1/20 0.36
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
RORC P51449 2/20 0.35
RAB9A P51151 4/20 0.35
NPC1 O15118 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
SLC13A5 Q86YT5 1/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18166513 0.93 MAPT (0.35) LMNAMAPTALDH1A1KDM4EMEN1
SCHEMBL18166511 0.91 MAPT (0.39) LMNAMAPTALDH1A1KDM4EMEN1
SCHEMBL1577100 0.87 LMNA (0.46) LMNAMAPTALDH1A1KDM4EMEN1
SCHEMBL28288263 0.84 RAB9A (0.43) LMNAMAPTALDH1A1KDM4EMEN1
SCHEMBL466267 0.82 RAB9A (0.52) MAPTALDH1A1KDM4EMEN1HTT
SCHEMBL1242129 0.81 RORC (0.41) LMNAMAPTALDH1A1KDM4ERORC
SCHEMBL27663353 0.81 SLC13A5 (0.46) LMNAMAPTRORCL3MBTL1SMN1; SMN2
SCHEMBL27871187 0.81 AOC3 (0.41) LMNAMAPTALDH1A1KDM4EMEN1
SCHEMBL19733281 0.81 MAPT (0.42) LMNAMAPTALDH1A1KDM4EMEN1
Urea SCHEMBL27646729 0.81 SMN1; SMN2 (0.46) LMNAMAPTMEN1KMT2ARORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3085661-B1 METHOD OF PRODUCING MICROFLUIDIC DEVICE JSR CORP (JP) 2017-12-27 EP disclosed