SCHEMBL197339

SCHEMBL197339

COC(=O)C(F)C(=O)C(F)F

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
CA14 Q9ULX7 2/20 0.34
CA12 O43570 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19492 0.83 SMN1; SMN2 (0.48) SMN1; SMN2CA14CA12KMT2AALDH1A1
SCHEMBL7638966 0.82 SMN1; SMN2 (0.41) SMN1; SMN2CA14CA12KMT2AALDH1A1
SCHEMBL237982 0.77
SCHEMBL28156637 0.77 SMN1; SMN2 (0.48) SMN1; SMN2CA14CA12KMT2AALDH1A1
SCHEMBL5076701 0.77 SMN1; SMN2 (0.41) SMN1; SMN2CA14CA12KMT2AALDH1A1
SCHEMBL224303 0.76
SCHEMBL353238 0.76
SCHEMBL457732 0.75 ALDH1A1 (0.42) KMT2AALDH1A1
SCHEMBL6323020 0.75 TSHR (0.40)
SCHEMBL8355254 0.75 SMN1; SMN2 (0.37) SMN1; SMN2CA14CA12KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025110550-A1 COMPLEX FOR GENE DELIVERY 전남대학교산학협력단 2025-05-30 WO claimed
CN-116632340-A Lithium ion electrolyte for inhibiting flatulence, preparation method thereof and electrochemical device 湖南法恩莱特新能源科技有限公司 2023-08-22 CN claimed
EP-0135491-B1 HERBICIDAL 2,6-BIS-FLUOROMETHYL-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTERS MONSANTO COMPANY (US) 1989-01-25 EP claimed
EP-0135491-A1 Herbicidal 2,6-bis-fluoromethyl-dihydropyridine-3,5-dicarboxylic acid esters MONSANTO COMPANY (US) 1985-03-27 EP claimed
JP-9227440-A None JP disclosed
US-12544382-B2 2, 4, 6-tri-substituted pyrimidine compound as ATR kinase inhibitor BEIJING TIDE PHARMACEUTICAL CO., LTD. (CN) 2026-02-10 US disclosed
WO-2025110550-A1 COMPLEX FOR GENE DELIVERY 전남대학교산학협력단 2025-05-30 WO disclosed
CN-118908902-A Preparation method of 3-trifluoromethyl-2-pyrazinecarboxylic acid ester compound 山东京博农化科技股份有限公司 2024-11-08 CN disclosed
CN-118619944-A 2,4, 6-Trisubstituted pyrimidine compounds as ATR kinase inhibitors 北京泰德制药股份有限公司 2024-09-10 CN disclosed
CN-118355007-A Herbicidal pyridone derivatives 先正达农作物保护股份公司 2024-07-16 CN disclosed
CN-114555720-B Antifouling additive 阿萨达股份公司 2024-04-05 CN disclosed
US-20240043593-A1 Fluorine-Containing Polymer CENTRAL GLASS COMPANY, LIMITED (JP) 2024-02-08 US disclosed
US-4826532-A HERBICIDES MONSANTO COMPANY (US) 1989-05-02 US disclosed
EP-0135491-B1 HERBICIDAL 2,6-BIS-FLUOROMETHYL-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTERS MONSANTO COMPANY (US) 1989-01-25 EP disclosed
EP-0278944-A1 Substituted 2,6-substituted pyridine compounds Monsanto Company (US) 1988-08-17 EP disclosed
EP-0278945-A2 Substituted 2,6-substituted pyridine compounds Monsanto Company (US) 1988-08-17 EP disclosed
US-4692184-A HERBICIDES MONSANTO COMPANY (US) 1987-09-08 US disclosed
EP-0135491-A1 Herbicidal 2,6-bis-fluoromethyl-dihydropyridine-3,5-dicarboxylic acid esters MONSANTO COMPANY (US) 1985-03-27 EP disclosed
EP-0133612-A2 Substituted 2,6-substituted pyridine compounds MONSANTO COMPANY (US) 1985-02-27 EP disclosed
US-4042603-A SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE UBE INDUSTRIES, LTD. (JA) 1977-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544382-B2 2, 4, 6-tri-substituted pyrimidine compound as ATR kinase inhibitor ATR, CHEK1, CHEK2 SMN1; SMN2 1690/4885CA14 4044/4885CA12 3912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.