Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | HSD17B1 | P14061 | 11/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 11/20 | 0.52 |
| ▸ | RXRA | P19793 | 2/20 | 0.49 |
| ▸ | RXRB | P28702 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20097508 | 0.96 | HSD17B1 (0.55) | KIF11HSD17B1HSD17B2RXRARXRB | |
| SCHEMBL26144030 | 0.90 | KIF11 (0.50) | KIF11HSD17B1HSD17B2RXRARXRB | |
| SCHEMBL12622623 | 0.88 | KIF11 (0.53) | KIF11HSD17B1HSD17B2RXRARXRB | |
| SCHEMBL5547288 | 0.84 | KIF11 (0.72) | KIF11RXRARXRBHDAC4HDAC2 | |
| SCHEMBL30023786 | 0.84 | KIF11 (0.72) | KIF11RXRARXRBHDAC4HDAC2 | |
| SCHEMBL27659191 | 0.81 | KIF11 (0.76) | KIF11RXRARXRBHDAC4HDAC2 | |
| SCHEMBL25451079 | 0.81 | HSD17B1 (0.48) | KIF11HSD17B1HSD17B2RXRARXRB | |
| SCHEMBL13483897 | 0.81 | CYP3A4 (0.55) | HSD17B1HSD17B2RXRARXRBCYP3A4 | |
| SCHEMBL17994290 | 0.81 | HSD17B1 (0.52) | KIF11HSD17B1HSD17B2CYP3A4CYP2C19 | |
| SCHEMBL25706667 | 0.79 | KIF11 (0.67) | KIF11RXRARXRBCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170365787-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2017-12-21 | — | — | US | disclosed |
| US-20170365787-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170365787-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | CRY1, NR2E3, LEF1 | KIF11 1106/4885HSD17B1 247/4885HSD17B2 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.