Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.48 |
| ▸ | RXRB | P28702 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | RAC2 | P15153 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24793867 | 0.99 | KDM4E (0.49) | RXRARXRBKDM4EATML3MBTL1 | |
| SCHEMBL18022256 | 0.96 | L3MBTL1 (0.51) | RXRARXRBKDM4EATML3MBTL1 | |
| SCHEMBL12000705 | 0.96 | KIF11 (0.49) | RXRARXRBKDM4EATML3MBTL1 | |
| SCHEMBL19129525 | 0.92 | L3MBTL1 (0.46) | RXRARXRBKDM4EATML3MBTL1 | |
| SCHEMBL19129607 | 0.92 | L3MBTL1 (0.46) | RXRARXRBKDM4EATML3MBTL1 | |
| SCHEMBL24793869 | 0.92 | KDM4E (0.49) | KDM4EATML3MBTL1KIF11SERPINE1 | |
| SCHEMBL20391671 | 0.92 | KDM4E (0.49) | KDM4EATML3MBTL1KIF11SERPINE1 | |
| SCHEMBL24792711 | 0.90 | KDM4E (0.49) | RXRARXRBKDM4EATML3MBTL1 | |
| SCHEMBL19129606 | 0.90 | L3MBTL1 (0.49) | RXRARXRBKDM4EATML3MBTL1 | |
| SCHEMBL26050697 | 0.90 | KDM4E (0.47) | RXRARXRBKDM4EATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9960357-B2 | Spiro-type compound and organic light emitting element comprising same | LG CHEM, LTD. (KR) | 2018-05-01 | — | — | US | disclosed |
| US-9960357-B2 | Spiro-type compound and organic light emitting element comprising same | LG CHEM, LTD. (KR) | 2018-05-01 | — | — | US | disclosed |
| US-20170365787-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2017-12-21 | — | — | US | disclosed |
| US-20170365787-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170365787-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | CRY1, NR2E3, LEF1 | RXRA 624/4885RXRB 1033/4885KDM4E 3359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.