Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25237284 | 0.82 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL9396654 | 0.79 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL28639403 | 0.78 | — | — | |
| SCHEMBL11344266 | 0.74 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL10424222 | 0.73 | MEN1 (0.35) | MEN1KMT2A | |
| Potassium Ion SCHEMBL752380 | 0.73 | ALDH1A1 (0.34) | MEN1KMT2A | |
| SCHEMBL2776281 | 0.72 | TSHR (0.36) | MEN1KMT2A | |
| SCHEMBL979981 | 0.72 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL274916 | 0.71 | ALDH1A1 (0.41) | — | |
| SCHEMBL11127704 | 0.71 | ALDH1A1 (0.59) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809332-B1 | COMPOSITIONS FOR MULTI-STEP DELIVERY OF HOT-SPOTS RADIATION TO CANCER CELLS | ONCOLOGIC INC (US) | 2011-12-14 | — | — | EP | disclosed |
| US-20110142756-A1 | Method And Composition For The Treatment Of Cancer By The Enzymatic Conversion Of Soluble Radioactive Toxic Precipitates In The Cancer | Rose, David S. (US) | 2011-06-16 | — | — | US | disclosed |
| US-7807136-B2 | Method and composition for the treatment of cancer by the enzymatic conversion of soluble radioactive toxic precipitates in the cancer | Rose, David S. (US) | 2010-10-05 | — | — | US | disclosed |
| US-20100062006-A9 | Method and composition for the treatment of cancer by the enzymatic conversion of soluble radioactive toxic precipitates in the cancer | MAYERS GEORGE L | 2010-03-11 | — | — | US | disclosed |
| US-7615221-B2 | Compositions and methods for treating cancer | ONCOLOGIC, INC. (US) | 2009-11-10 | — | — | US | disclosed |
| EP-1809332-A2 | COMPOSITIONS FOR MULTI-STEP DELIVERY OF HOT-SPOTS RADIATION TO CANCER CELLS | Oncologic, Inc. (US) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006010165-A2 | COMPOSITIONS FOR MULTI-STEP DELIVERY OF HOT-SPOTS RADIATION TO CANCER CELLS | ONCOLOGIC, INC. (US) | 2006-01-26 | — | — | WO | disclosed |
| US-20060018908-A1 | Compositions and methods for treating cancer | ROSE, DAVID STUART | 2006-01-26 | — | — | US | disclosed |
| US-20050058652-A1 | Method and composition for the treatment of cancer by the enzymatic conversion of soluble radioactive toxic precipitates in the cancer | ROSE, DAVID STUART | 2005-03-17 | — | — | US | disclosed |