Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 2/20 | 0.32 |
| ▸ | SI | P14410 | 2/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2139646 | 0.81 | HSP90AB1 (0.40) | TSHRHSP90AB1GAATP53CYP4F2 | |
| SCHEMBL21160122 | 0.78 | TP53 (0.37) | TSHRHSP90AB1GAATP53CYP4F2 | |
| SCHEMBL11468517 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL2142693 | 0.72 | ALDH1A1 (0.38) | SMN1; SMN2LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL13331957 | 0.71 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL12616313 | 0.71 | HSP90AB1 (0.37) | TSHRHSP90AB1GAATP53CYP4F2 | |
| SCHEMBL4291847 | 0.70 | — | — | |
| SCHEMBL2141828 | 0.68 | GAA (0.40) | GAASMN1; SMN2ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL1783717 | 0.68 | — | — | |
| SCHEMBL12616276 | 0.65 | HSP90AB1 (0.36) | TSHRHSP90AB1GAATP53CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362155-A1 | CIRCULAR ECONOMY METHODS OF PREPARING UNSATURATED COMPOUNDS | INTERNATIONAL FLAVORS AND FRAGRANCES INC. | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362155-A1 | CIRCULAR ECONOMY METHODS OF PREPARING UNSATURATED COMPOUNDS | FADS1, SCD, FASN | TSHR 3871/4885HSP90AB1 3723/4885GAA 1414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.