SCHEMBL19736611

SCHEMBL19736611

CCCC(C)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 0.52
TSHR P16473 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ACACB O00763 1/20 0.43
ACACA Q13085 1/20 0.43
RIPK1 Q13546 1/20 0.43
SLC7A5 Q01650 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL6014529 0.88 LTA4H (0.56) LTA4HTSHRALDH1A1LMNAACACB
SCHEMBL18745964 0.87 ALDH1A1 (0.49) TSHRALDH1A1ACACASLC7A5
SCHEMBL10162228 0.85 ALDH1A1 (0.54) LTA4HTSHRALDH1A1ACACBACACA
SCHEMBL27629422 0.84 PTGS1 (0.55) LTA4HTSHRALDH1A1LMNASMN1; SMN2
SCHEMBL27629258 0.84 FFAR1 (0.43) LTA4H
SCHEMBL9141663 0.84 ALDH1A1 (0.50) TSHRALDH1A1SMN1; SMN2
SCHEMBL11489544 0.84 LTA4H (0.50) LTA4HALDH1A1RIPK1SLC7A5
SCHEMBL5544471 0.84 LTA4H (0.44) LTA4HTSHRACACBACACARIPK1
SCHEMBL16542088 0.83 ACACA (0.41) LTA4HSMN1; SMN2ACACBACACA
SCHEMBL8692048 0.83 FFAR1 (0.54) LTA4HTSHRALDH1A1ACACBACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170360924-A1 HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS ACADEMIA SINICA (TW) 2017-12-21 US disclosed
CN-102532162-B 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMA CO LTD 2015-05-27 CN disclosed
CN-101255170-A 2,3-dihydroimidazo[2,1-b]oxazole compound OTSUKA PHARMA CO LTD (JP) 2008-09-03 CN disclosed
CN-101172981-A 2,3-dihydroimidazo[2,1-b]oxazole compound OTSUKA PHARMA CO LTD (JP) 2008-05-07 CN disclosed
CN-100366624-C 2, 3-dihydro-6-nitroimidazo [2,1-b ] * azole compounds OTSUKA PHARMA CO LTD (JP) 2008-02-06 CN disclosed
CN-1705670-A 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds OTSUKA PHARMA CO LTD (JP) 2005-12-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170360924-A1 HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS UGCG, GALK1, B3GAT3 LTA4H 361/4885TSHR 2390/4885ALDH1A1 2338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.