Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19751510 | 0.81 | ALDH1A1 (0.49) | ALDH1A1GAAHSD17B10MAPTADRA2A | |
| SCHEMBL15828688 | 0.81 | MAPT (0.36) | ALDH1A1GAAHSD17B10MAPTADRA2A | |
| SCHEMBL30954167 | 0.79 | FABP6 (0.41) | ALDH1A1GAAHSD17B10MAPTADRA2A | |
| SCHEMBL19751511 | 0.79 | ALDH1A1 (0.46) | ALDH1A1GAAHSD17B10MAPTADRA2A | |
| SCHEMBL19751518 | 0.79 | ALDH1A1 (0.46) | ALDH1A1GAAHSD17B10MAPTADRA2A | |
| SCHEMBL19751547 | 0.79 | ALDH1A1 (0.46) | ALDH1A1GAAHSD17B10MAPTADRA2A | |
| SCHEMBL5246441 | 0.79 | ALDH1A1 (0.46) | ALDH1A1GAAHSD17B10MAPTADRA2A | |
| SCHEMBL19737593 | 0.78 | MAPT (0.36) | ALDH1A1GAAHSD17B10MAPTADRA2A | |
| SCHEMBL4870090 | 0.78 | GRM1 (0.36) | ALDH1A1GAAHSD17B10MAPTADRA2A | |
| SCHEMBL19751509 | 0.76 | ALDH1A1 (0.44) | ALDH1A1GAAHSD17B10MAPTADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |
| EP-2751083-B1 | QUINOLONE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2017-12-27 | — | — | EP | disclosed |
| US-20170362180-A1 | QUINOLONE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362180-A1 | QUINOLONE COMPOUND | HAX1, NQO2, NHERF1 | ALDH1A1 1445/4885GAA 3410/4885HSD17B10 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.