Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28190730 | 0.81 | NOS3 (0.55) | NOS3NOS2MAOAALDH1A1KDM4E | |
| SCHEMBL16849921 | 0.78 | NOS3 (0.45) | NOS3NOS2MAOAALDH1A1KDM4E | |
| SCHEMBL2226165 | 0.78 | NOS3 (0.45) | NOS3NOS2MAOAALDH1A1KDM4E | |
| SCHEMBL29498353 | 0.78 | NOS3 (0.52) | NOS3NOS2MAOAALDH1A1KDM4E | |
| SCHEMBL18044406 | 0.78 | NOS3 (0.56) | NOS3NOS2MAOAALDH1A1KDM4E | |
| SCHEMBL6207612 | 0.78 | NOS3 (0.52) | NOS3NOS2MAOAALDH1A1KDM4E | |
| SCHEMBL29384557 | 0.77 | MAPK10 (0.55) | NOS3NOS2MAOAALDH1A1KDM4E | |
| SCHEMBL163051 | 0.77 | MAPK10 (0.55) | NOS3NOS2MAOAALDH1A1KDM4E | |
| SCHEMBL31219707 | 0.76 | NOS3 (0.59) | NOS3NOS2MAOAALDH1A1KDM4E | |
| SCHEMBL12352549 | 0.76 | NOS3 (0.59) | NOS3NOS2MAOAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846920-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| US-8846920-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| US-8846920-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| EP-1675929-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-06-22 | — | — | EP | disclosed |
| EP-1675929-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-06-22 | — | — | EP | disclosed |
| US-20100331506-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
| US-20100331506-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
| US-20100331506-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
| US-7820822-B2 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | MERCK PATENT GMBH (DE) | 2010-10-26 | — | — | US | disclosed |
| US-7820822-B2 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | MERCK PATENT GMBH (DE) | 2010-10-26 | — | — | US | disclosed |
| US-7820822-B2 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | MERCK PATENT GMBH (DE) | 2010-10-26 | — | — | US | disclosed |
| US-20070034863-A1 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | UDC IRELAND LIMITED (IE) | 2007-02-15 | — | — | US | disclosed |
| US-20070034863-A1 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | UDC IRELAND LIMITED (IE) | 2007-02-15 | — | — | US | disclosed |
| US-20070034863-A1 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | UDC IRELAND LIMITED (IE) | 2007-02-15 | — | — | US | disclosed |
| EP-1675929-A1 | METAL COMPLEXES | MERCK PATENT GmbH (DE) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005033244-A1 | METAL COMPLEXES | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2005-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331506-A1 | METAL COMPLEXES | SOD1, AP1M1, AP2M1 | NOS3 2809/4885NOS2 2706/4885MAOA 757/4885 |
| US-20070034863-A1 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | NISCH, CISD1, AFF1 | NOS3 1383/4885NOS2 976/4885MAOA 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.