Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.56 |
| ▸ | INPPL1 | O15357 | 8/20 | 0.53 |
| ▸ | INPP5A | Q14642 | 4/20 | 0.53 |
| ▸ | INPP5B | P32019 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 3/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8384709 | 0.89 | SRC (0.63) | SRCINPPL1INPP5AINPP5BKDM4E | |
| SCHEMBL842728 | 0.79 | INPPL1 (0.63) | SRCINPPL1INPP5AINPP5BKDM4E | |
| SCHEMBL29655758 | 0.77 | INPPL1 (0.59) | SRCINPPL1INPP5AINPP5BKDM4E | |
| SCHEMBL522291 | 0.77 | INPPL1 (0.59) | SRCINPPL1INPP5AINPP5BKDM4E | |
| SCHEMBL16724689 | 0.76 | ERN1 (0.41) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL16732140 | 0.76 | ERN1 (0.41) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL743608 | 0.76 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDHSD17B10ERN1 | |
| SCHEMBL28923677 | 0.76 | ERN1 (0.41) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL28895404 | 0.75 | INPPL1 (0.57) | SRCINPPL1INPP5AINPP5BKDM4E | |
| Ammonia Solution, Strong SCHEMBL11748950 | 0.75 | INPPL1 (0.57) | SRCINPPL1INPP5AINPP5BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787430-B2 | Hemoglobin modifier compounds and uses thereof | FRONTHERA U.S. PHARMACEUTICALS LLC (US) | 2020-09-29 | — | — | US | disclosed |
| US-20190330181-A1 | HEMOGLOBIN MODIFIER COMPOUNDS AND USES THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2019-10-31 | — | — | US | disclosed |
| WO-2017218960-A1 | HEMOGLOBIN MODIFIER COMPOUNDS AND USES THEREOF | FRONTHERA U.S. PHARMACEUTICALS LLC (US) | 2017-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330181-A1 | HEMOGLOBIN MODIFIER COMPOUNDS AND USES THEREOF | HBB, HBG1, HBG2 | SRC 2806/4885INPPL1 3661/4885INPP5A 2436/4885 |
| US-10787430-B2 | Hemoglobin modifier compounds and uses thereof | HBB, HBG1, HBG2 | SRC 2806/4885INPPL1 3661/4885INPP5A 2436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.