Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19741724 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPK1KMT2ASIRT2PSMB5 | |
| SCHEMBL19741660 | 0.83 | KDM5A (0.39) | SMN1; SMN2MAPK1SIRT2PSMB5HPGD | |
| SCHEMBL19741664 | 0.83 | KDM5A (0.39) | SMN1; SMN2MAPK1SIRT2PSMB5HPGD | |
| SCHEMBL19664325 | 0.71 | KDM5B (0.44) | SIRT2PSMB5KDM5BKDM4AKDM4B | |
| SCHEMBL16291524 | 0.71 | KDM5B (0.44) | SIRT2PSMB5KDM5BKDM4AKDM4B | |
| SCHEMBL17144516 | 0.70 | ALDH1A1 (0.39) | SMN1; SMN2MAPK1KMT2APSMB5ALDH1A1 | |
| SCHEMBL17144518 | 0.66 | TRPV3 (0.50) | ALDH1A1MAPTKDM5BKDM4AKDM4B | |
| SCHEMBL17144520 | 0.66 | TRPV3 (0.50) | ALDH1A1MAPTKDM5BKDM4AKDM4B | |
| SCHEMBL19741637 | 0.64 | KDM4C (0.40) | SMN1; SMN2KMT2AALDH1A1MEN1HPGD | |
| SCHEMBL19741636 | 0.64 | KDM4C (0.40) | SMN1; SMN2KMT2AALDH1A1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170369444-A1 | INHIBITORS OF HISTONE DEMETHYLASES | EPITHERAPEUTICS APS (DK) | 2017-12-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369444-A1 | INHIBITORS OF HISTONE DEMETHYLASES | KDM1B, KDM3A, KDM1A | SMN1; SMN2 2826/4885MAPK1 3575/4885KMT2A 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.