SCHEMBL19742233

SCHEMBL19742233

CC(C)(C)OC(=O)C(CCCCNC(=O)n1ccnc1)NC(=O)NC(CCC(=O)O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 19/20 0.49
DGAT1 O75907 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19742232 1.00 FOLH1 (0.49) FOLH1DGAT1
SCHEMBL29714503 0.90 TDP1 (0.41)
SCHEMBL19756829 0.84 TDP1 (0.39)
SCHEMBL23067828 0.83 TBXAS1 (0.38)
SCHEMBL29129053 0.81 KMT2A (0.47)
SCHEMBL29613413 0.81 TDP1 (0.52)
SCHEMBL18135317 0.80 KMT2A (0.43)
SCHEMBL29750399 0.79 NOD1 (0.47)
SCHEMBL22712971 0.76 FOLH1 (0.67) FOLH1
SCHEMBL18145839 0.76 FOLH1 (0.67) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4249005-A2 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS Cornell University (US) 2023-09-27 EP disclosed
EP-3493856-B1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS UNIV CORNELL (US) 2023-08-09 EP disclosed
US-20220194904-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS CORNELL UNIVERSITY (US) 2022-06-23 US disclosed
US-20200317588-A1 18F-LABELED PEPTIDE LIGANDS USEFUL IN PET AND CERENKOV LUMINESCENE IMAGING CORNELL UNIVERSITY (US) 2020-10-08 US disclosed
US-20170369454-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS UNIV CORNELL (US) 2017-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200317588-A1 18F-LABELED PEPTIDE LIGANDS USEFUL IN PET AND CERENKOV LUMINESCENE IMAGING VIP, CALCA, GLP1R FOLH1 33/4885DGAT1 4569/4885
US-20170369454-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS PSMA3, FOLH1, PSMA1 FOLH1 2/4885DGAT1 4251/4885
US-20220194904-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS PSMA3, FOLH1, PSMA1 FOLH1 2/4885DGAT1 4251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.