Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17354454 | 0.85 | KMT2A (1.00) | MEN1KMT2ATDP1L3MBTL1POLB | |
| SCHEMBL28710997 | 0.83 | LMNA (0.68) | MEN1KMT2ATDP1L3MBTL1POLB | |
| SCHEMBL1285869 | 0.83 | ALDH1A1 (0.73) | KMT2AL3MBTL1POLBALDH1A1LMNA | |
| SCHEMBL743064 | 0.83 | ALDH1A1 (0.73) | KMT2AL3MBTL1POLBALDH1A1LMNA | |
| SCHEMBL1285890 | 0.83 | ALDH1A1 (0.73) | KMT2AL3MBTL1POLBALDH1A1LMNA | |
| SCHEMBL13761364 | 0.82 | ALDH1A1 (0.66) | MEN1KMT2ATDP1L3MBTL1POLB | |
| SCHEMBL12461860 | 0.81 | ALDH1A1 (0.71) | KMT2AL3MBTL1POLBALDH1A1LMNA | |
| SCHEMBL20022689 | 0.81 | ALDH1A1 (0.71) | KMT2AL3MBTL1POLBALDH1A1LMNA | |
| SCHEMBL16348943 | 0.81 | ALDH1A1 (0.71) | KMT2AL3MBTL1POLBALDH1A1LMNA | |
| SCHEMBL9829574 | 0.81 | ALDH1A1 (0.65) | MEN1KMT2ATDP1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846920-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| EP-1675929-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-06-22 | — | — | EP | disclosed |
| US-20100331506-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
| US-7820822-B2 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | MERCK PATENT GMBH (DE) | 2010-10-26 | — | — | US | disclosed |
| US-20070034863-A1 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | UDC IRELAND LIMITED (IE) | 2007-02-15 | — | — | US | disclosed |
| EP-1675929-A1 | METAL COMPLEXES | MERCK PATENT GmbH (DE) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005033244-A1 | METAL COMPLEXES | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2005-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331506-A1 | METAL COMPLEXES | SOD1, AP1M1, AP2M1 | MEN1 354/4885KMT2A 1588/4885TDP1 3173/4885 |
| US-20070034863-A1 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | NISCH, CISD1, AFF1 | MEN1 1841/4885KMT2A 3293/4885TDP1 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.