Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415045 | 0.82 | GRM5 (0.50) | NPC1SMN1; SMN2RAB9AHTTMEN1 | |
| SCHEMBL27660967 | 0.81 | NPC1 (0.48) | KDM4ENPSR1L3MBTL1NPC1TLR8 | |
| SCHEMBL19897481 | 0.79 | BACE1 (0.54) | NPC1TLR8UTS2RTLR7KDM6B | |
| SCHEMBL30692781 | 0.79 | NPC1 (0.47) | KDM4ENPSR1L3MBTL1NPC1TLR8 | |
| SCHEMBL11149010 | 0.77 | HTT (0.54) | KDM4EL3MBTL1NPC1TLR8TLR7 | |
| SCHEMBL14031588 | 0.77 | TLR8 (0.50) | KDM4ENPSR1L3MBTL1TLR8UTS2R | |
| SCHEMBL516228 | 0.76 | UTS2R (0.49) | KDM4ENPSR1L3MBTL1NPC1TLR8 | |
| SCHEMBL18992277 | 0.76 | NPC1 (0.43) | NPSR1L3MBTL1NPC1TLR8UTS2R | |
| SCHEMBL309485 | 0.75 | TLR8 (0.53) | KDM4ENPSR1L3MBTL1TLR8UTS2R | |
| SCHEMBL4711248 | 0.75 | BACE1 (0.53) | NPSR1L3MBTL1NPC1TLR8UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816086-B2 | Process for preparing cannabinoid receptor ligands | ABBVIE INC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8816086-B2 | Process for preparing cannabinoid receptor ligands | ABBVIE INC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8816086-B2 | Process for preparing cannabinoid receptor ligands | ABBVIE INC. (US) | 2014-08-26 | — | — | US | disclosed |
| WO-2011075525-A1 | PROCESS FOR PREPARING CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011075525-A1 | PROCESS FOR PREPARING CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | WO | disclosed |
| US-20110144343-A1 | PROCESS FOR PREPARING CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2011-06-16 | — | — | US | disclosed |
| US-20110144343-A1 | PROCESS FOR PREPARING CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2011-06-16 | — | — | US | disclosed |
| US-20110144343-A1 | PROCESS FOR PREPARING CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144343-A1 | PROCESS FOR PREPARING CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, NPY1R | KDM4E 1824/4885NPSR1 11/4885L3MBTL1 4497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.