SCHEMBL516228

SCHEMBL516228

CCCCCNc1cccnc1NCCCCC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 6/20 0.49
TLR8 Q9NR97 1/20 0.48
TLR7 Q9NYK1 1/20 0.48
NPSR1 Q6W5P4 2/20 0.48
S1PR2 O95136 1/20 0.48
LMNA P02545 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
KCNH2 Q12809 1/20 0.43
CCNB2 O95067 1/20 0.43
CDK1 P06493 1/20 0.43
CCNB1 P14635 1/20 0.43
CCNB3 Q8WWL7 1/20 0.43
NPC1 O15118 1/20 0.43
GRM5 P41594 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24846448 0.90 UTS2R (0.44) UTS2RTLR8TLR7NPSR1S1PR2
SCHEMBL1977303 0.87 KDM4E (0.57) UTS2RTLR8TLR7KDM4EALDH1A1
SCHEMBL9573464 0.84 L3MBTL1 (0.42) UTS2RTLR8TLR7NPSR1S1PR2
SCHEMBL7961503 0.84 L3MBTL1 (0.42) UTS2RTLR8TLR7NPSR1S1PR2
SCHEMBL8884296 0.82 BDKRB1 (0.49) L3MBTL1
SCHEMBL11666495 0.81 UTS2R (0.48) UTS2RTLR8TLR7NPSR1S1PR2
SCHEMBL4711248 0.81 BACE1 (0.53) UTS2RTLR8TLR7NPSR1S1PR2
SCHEMBL11666498 0.81 NPC1 (0.42) UTS2RTLR8TLR7NPSR1S1PR2
SCHEMBL8510590 0.81 L3MBTL1 (0.45) UTS2RTLR8TLR7NPSR1S1PR2
SCHEMBL1978099 0.81 HIF1A (0.44) LMNASMN1; SMN2KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8354097-B2 Cosmetic composition forming after application a supramolecular polymer L'OREAL (FR) 2013-01-15 US claimed
US-20120027698-A9 COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS L'OREAL S.A. 2012-02-02 US claimed
US-7862805-B2 Cosmetic composition forming after application a supramolecular polymer L'OREAL (FR) 2011-01-04 US claimed
US-20100278764-A1 COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS L'OREAL S.A. 2010-11-04 US claimed
US-20100247466-A1 COSMETIC COMPOSITION FORMING AFTER APPLICATION A SUPRAMOLECULAR POLYMER L'OREAL (FR) 2010-09-30 US claimed
US-20070264208-A1 Cosmetic and/or pharmaceutical composition comprising at least one copolymer comprising at least one ionizable group, and cosmetic treatment process L'OREAL S.A. (FR) 2007-11-15 US claimed
EP-1392222-B1 COSMETIC COMPOSITION FORMING AFTER APPLICATION A SUPRAMOLECULAR POLYMER OREAL (FR) 2007-09-05 EP claimed
JP-3951000-B2 2007-08-01 JP claimed
EP-1797868-A1 Cosmetic composition comprising a (thio)urethane/(thio)urea copolymer capable of forming at least 3 hydrogen bonds, and process for cosmetic treatment L'Oréal (FR) 2007-06-20 EP claimed
EP-1797867-A1 Cosmetic or pharmaceutical composition comprising a copolymer containing at least one ionisable group, and cosmetic treatment L'Oréal (FR) 2007-06-20 EP claimed
JP-2005520777-A 2005-07-14 JP claimed
US-20040161394-A1 Cosmetic composition forming after application a supramolecular polymer L'OREAL (FR) 2004-08-19 US claimed
EP-1392222-A1 COSMETIC COMPOSITION FORMING AFTER APPLICATION A SUPRAMOLECULAR POLYMER L'OREAL (FR) 2004-03-03 EP claimed
WO-2002098377-A1 COSMETIC COMPOSITION FORMING AFTER APPLICATION A SUPRAMOLECULAR POLYMER L'OREAL (FR) 2002-12-12 WO claimed
EP-3548544-B1 AQUEOUS DISPERSION OF POLYALKENE SUPRAMOLECULAR POLYMER AND ITS USE IN COSMETICS OREAL (FR) 2021-07-21 EP disclosed
US-10973751-B2 Hair dyeing process comprising a pigment and an aqueous dispersion of supramolecular polymer L'OREAL (FR) 2021-04-13 US disclosed
US-20200108007-A1 HAIR DYEING PROCESS COMPRISING A PIGMENT AND AN AQUEOUS DISPERSION OF SUPRAMOLECULAR POLYMER L'OREAL (FR) 2020-04-09 US disclosed
US-5863919-A Lock and key micelles and monomer building blocks therefor UNIVERSITY OF SOUTH FLORIDA (US) 1999-01-26 US disclosed
US-5650101-A Lock and key micelles UNIVERSITY OF SOUTH FLORIDA (US) 1997-07-22 US disclosed
EP-0771190-A1 LOCK AND KEY MICELLES UNIVERSITY OF SOUTH FLORIDA (US) 1997-05-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10973751-B2 Hair dyeing process comprising a pigment and an aqueous dispersion of supramolecular polymer TYR, NACA, POLR1C UTS2R 2848/4885TLR8 3795/4885TLR7 3115/4885
US-20070264208-A1 Cosmetic and/or pharmaceutical composition comprising at least one copolymer comprising at least one ionizable group, and cosmetic treatment process KRT18, DSG1, DSC1 UTS2R 4763/4885TLR8 3680/4885TLR7 3435/4885
US-20120027698-A9 COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS KRT18, DSG1, DSC1 UTS2R 4752/4885TLR8 3855/4885TLR7 3523/4885
US-20200108007-A1 HAIR DYEING PROCESS COMPRISING A PIGMENT AND AN AQUEOUS DISPERSION OF SUPRAMOLECULAR POLYMER TYR, NACA, POLR1C UTS2R 2848/4885TLR8 3795/4885TLR7 3115/4885
US-20040161394-A1 Cosmetic composition forming after application a supramolecular polymer KRT18, DSG1, CUTA UTS2R 4644/4885TLR8 2540/4885TLR7 1147/4885
US-20100278764-A1 COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS KRT18, DSG1, DSC1 UTS2R 4752/4885TLR8 3855/4885TLR7 3523/4885
US-20100247466-A1 COSMETIC COMPOSITION FORMING AFTER APPLICATION A SUPRAMOLECULAR POLYMER KRT18, CUTA, DSG1 UTS2R 4761/4885TLR8 2682/4885TLR7 1484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.