Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19897481 | 0.95 | BACE1 (0.54) | BACE1TLR8TLR7NPC1SHMT2 | |
| SCHEMBL516228 | 0.81 | UTS2R (0.49) | TLR8TLR7NPC1UTS2RS1PR2 | |
| SCHEMBL9977872 | 0.81 | BACE1 (0.50) | BACE1TLR7SHMT2HSP90AA1HSP90AB1 | |
| SCHEMBL3060454 | 0.80 | BACE1 (0.61) | BACE1SHMT2NOS3NOS1NOS2 | |
| SCHEMBL8510590 | 0.80 | L3MBTL1 (0.45) | TLR8TLR7NPC1UTS2RHSP90AA1 | |
| SCHEMBL11666498 | 0.80 | NPC1 (0.42) | TLR8TLR7NPC1UTS2RHSP90AA1 | |
| SCHEMBL9977915 | 0.80 | BACE1 (0.49) | BACE1TLR8TLR7SHMT2HSP90AA1 | |
| SCHEMBL1170549 | 0.79 | TLR8 (0.49) | TLR8NPC1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL29922455 | 0.79 | TLR8 (0.49) | TLR8NPC1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL24846448 | 0.79 | UTS2R (0.44) | TLR8TLR7NPC1UTS2RHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982749-B1 | Novel hair colouring compositions for use in oxidative hair dyeing | PROCTER & GAMBLE (US) | 2013-04-17 | — | — | EP | disclosed |
| CN-101137345-B | Novel hair coloring compositions for oxidative hair dyeing | PROCTER & GAMBLE | 2012-10-31 | — | — | CN | disclosed |
| EP-1982749-A3 | Novel hair colouring compositions for use in oxidative hair dyeing | The Procter and Gamble Company (US) | 2008-11-12 | — | — | EP | disclosed |
| EP-1982749-A2 | Novel hair colouring compositions for use in oxidative hair dyeing | The Procter and Gamble Company (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1982749-A2 | Novel hair colouring compositions for use in oxidative hair dyeing | The Procter and Gamble Company (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1982748-A2 | Novel hair colouring compositions for use in oxidative hair dyeing | The Procter & Gamble (US) | 2008-10-22 | — | — | EP | disclosed |
| CN-101137345-A | Novel hair coloring compositions for oxidative hair dyeing | PROCTER & GAMBLE (US) | 2008-03-05 | — | — | CN | disclosed |
| US-7303592-B2 | Hair coloring compositions for use in oxidative hair dyeing | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | disclosed |
| US-7303592-B2 | Hair coloring compositions for use in oxidative hair dyeing | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | disclosed |
| EP-1855644-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | The Procter and Gamble Company (US) | 2007-11-21 | — | — | EP | disclosed |
| EP-1855644-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | The Procter and Gamble Company (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006099115-A3 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | PROCTER & GAMBLE (US) | 2006-12-21 | — | — | WO | disclosed |
| WO-2006099115-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-21 | — | — | WO | disclosed |
| WO-2006099115-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-21 | — | — | WO | disclosed |
| US-20050188480-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2005-09-01 | — | — | US | disclosed |
| US-20050188480-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2005-09-01 | — | — | US | disclosed |
| US-4358454-A | ANTIULCER AGENT | SCHERING CORPORATION (US) | 1982-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050188480-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | COXFA4L2, TYR, GPX4 | BACE1 2194/4885TLR8 4313/4885TLR7 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.