Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 5/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18319652 | 0.88 | LIPG (0.39) | HIF1ALIPGROCK1LPLP4HB | |
| SCHEMBL27159868 | 0.84 | KDM4E (0.47) | HIF1ALIPGROCK1LPLF11 | |
| SCHEMBL17418789 | 0.84 | ROCK1 (0.53) | HIF1ALIPGROCK1LPLP4HB | |
| SCHEMBL1684669 | 0.81 | LIPG (0.53) | LIPGLPLP4HBF11F2 | |
| SCHEMBL21682668 | 0.81 | HIF1A (0.50) | HIF1ALIPGROCK1LPLF11 | |
| SCHEMBL4604189 | 0.78 | LIPG (0.52) | LIPGLPLP4HBCA9CA12 | |
| SCHEMBL12502664 | 0.78 | HIF1A (0.48) | HIF1ALIPGROCK1LPLP4HB | |
| SCHEMBL4815568 | 0.78 | LPL (0.44) | HIF1ALIPGROCK1LPLF11 | |
| SCHEMBL23123642 | 0.77 | LIPG (0.41) | HIF1ALIPGROCK1LPLP4HB | |
| SCHEMBL29817025 | 0.77 | LIPG (0.41) | HIF1ALIPGROCK1LPLP4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017220431-A1 | FUSED PYRAZOLE DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2017-12-28 | — | — | WO | disclosed |