SCHEMBL19743717

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5559163	0.85	GPR35 (0.62)	LOXL2GPR35KDM4EUSP2CSNK2A2
	SCHEMBL28290283	0.84	GPR35 (0.47)	LOXL2GPR35ALDH1A1KMT2AKDM4E
	SCHEMBL10358942	0.84	GPR35 (0.61)	LOXL2GPR35KDM4EUSP2CSNK2A2
	SCHEMBL8122752	0.83	LOXL2 (0.56)	LOXL2GPR35ALDH1A1KMT2AKDM4E
	SCHEMBL8107475	0.83	GPR35 (0.48)	GPR35ALDH1A1KMT2AKDM4EUSP2
	SCHEMBL8121513	0.80	GPR35 (0.49)	LOXL2GPR35ALDH1A1KMT2AKDM4E
	SCHEMBL10509414	0.80	ALDH1A1 (0.64)	ALDH1A1KMT2AMAOALCKMAOB
	SCHEMBL8827815	0.79	ALDH1A1 (0.68)	GPR35ALDH1A1KMT2AMAOAKDM4E
	SCHEMBL30987790	0.78	KDM4E (0.60)	ALDH1A1KMT2AKDM4ECSNK2A2CSNK2B
	SCHEMBL7628829	0.78	GPR35 (0.78)	GPR35ALDH1A1KMT2AMAOAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.