Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | ACHE | P22303 | 3/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986215 | 1.00 | METTL3 (0.65) | METTL3LMNAMAOBACHEBCHE | |
| SCHEMBL21174951 | 0.99 | LMNA (0.66) | METTL3LMNAMAOBACHEBCHE | |
| SCHEMBL28997464 | 0.89 | ACHE (0.72) | METTL3LMNAMAOBACHEBCHE | |
| SCHEMBL21175008 | 0.89 | LMNA (0.63) | METTL3LMNAMAOBACHEBCHE | |
| SCHEMBL21174996 | 0.88 | LMNA (0.62) | METTL3LMNAMAOBACHEBCHE | |
| SCHEMBL21174991 | 0.88 | ACHE (0.74) | METTL3LMNAMAOBACHEBCHE | |
| SCHEMBL21174960 | 0.87 | LMNA (0.60) | METTL3LMNAMAOBACHEBCHE | |
| SCHEMBL29985626 | 0.85 | AKR1B1 (0.54) | METTL3MAOBACHEMAOAPOLB | |
| SCHEMBL19744394 | 0.85 | AKR1B1 (0.54) | METTL3MAOBACHEMAOAPOLB | |
| SCHEMBL19744231 | 0.85 | MAOB (0.57) | METTL3MAOBACHEBCHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641864-B | Anti-infective agents | 邓迪大学 | 2023-04-04 | — | — | CN | disclosed |
| US-11485720-B2 | Anti-infective agents | UNIVERSITY OF DUNDEE (GB) | 2022-11-01 | — | — | US | disclosed |
| US-20210101877-A1 | ANTI-INFECTIVE AGENTS | UNIVERSITY OF DUNDEE (GB) | 2021-04-08 | — | — | US | disclosed |
| US-20190225592-A1 | ANTI-INFECTIVE AGENTS | UNIVERSITY OF DUNDEE (GB) | 2019-07-25 | — | — | US | disclosed |
| EP-3472141-A1 | ANTI-INFECTIVE AGENTS | University Of Dundee (GB) | 2019-04-24 | — | — | EP | disclosed |
| CN-109641864-A | ANTI-INFECTIVE AGENTS | 邓迪大学 | 2019-04-16 | — | — | CN | disclosed |
| WO-2017221002-A1 | ANTI-INFECTIVE AGENTS | UNIVERSITY OF DUNDEE (GB) | 2017-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11485720-B2 | Anti-infective agents | C1R, RRS1, ARG1 | METTL3 4284/4885LMNA 2536/4885MAOB 2696/4885 |
| US-20210101877-A1 | ANTI-INFECTIVE AGENTS | C1R, RRS1, ARG1 | METTL3 4284/4885LMNA 2536/4885MAOB 2696/4885 |
| US-20190225592-A1 | ANTI-INFECTIVE AGENTS | C1R, ARG1, MSR1 | METTL3 4440/4885LMNA 2610/4885MAOB 2283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.