Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PTPRB | P23467 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CD69 | Q07108 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645298 | 0.80 | ALOX15 (0.65) | ALOX15PTPN7HSD17B10HPGDPTPRB | |
| SCHEMBL19745546 | 0.78 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8528993 | 0.78 | PTPN7 (0.58) | ALOX15PTPN7HSD17B10LMNAALDH1A1 | |
| SCHEMBL3138757 | 0.76 | ALOX15 (0.50) | ALOX15PTPN7HSD17B10HPGDPTPRB | |
| SCHEMBL6516217 | 0.76 | HPGD (0.62) | ALOX15PTPN7HSD17B10HPGDPTPRB | |
| SCHEMBL9522071 | 0.76 | THRA (0.56) | ALOX15PTPN7HSD17B10HPGDPTPRB | |
| SCHEMBL3301562 | 0.76 | PPARD (0.66) | ALOX15PTPN7HSD17B10HPGDLMNA | |
| SCHEMBL8528987 | 0.76 | PTGDR2 (0.55) | ALOX15PTPN7HSD17B10LMNAALDH1A1 | |
| SCHEMBL19745151 | 0.76 | GAA (0.50) | HPGDLMNAALDH1A1TSHRFFAR1 | |
| SCHEMBL11095614 | 0.75 | HMGB1 (0.51) | HSD17B10HPGDPTPRBLMNATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017222921-A1 | 2-HYDROXYISOPHTHALIC ACID AND ITS DERIVATIVES: METHODS OF MAKING AND APPLICATIONS | XAVIER UNIVERSITY OF LOUISIANA (US) | 2017-12-28 | — | — | WO | disclosed |