SCHEMBL197459

SCHEMBL197459

CCCOC(=O)c1ccc(Cl)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.70
TSHR P16473 3/20 0.70
ESR1 P03372 2/20 0.70
TDP1 Q9NUW8 2/20 0.70
CHRM1 P11229 1/20 0.70
SLC6A2 P23975 1/20 0.70
KDR P35968 1/20 0.70
LMNA P02545 4/20 0.67
GAA P10253 1/20 0.63
STS P08842 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C19 P33261 2/20 0.56
CYP2D6 P10635 1/20 0.56
MAPK1 P28482 1/20 0.56
NR1H2 P55055 1/20 0.56
RNASEL Q05823 1/20 0.56
HPGD P15428 2/20 0.56
CYP3A4 P08684 1/20 0.54
CYP2C9 P11712 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49950 0.90 ALDH1A1 (0.84) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL6057147 0.89 ESR1 (0.72) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL27647501 0.88 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1
Methane SCHEMBL27699232 0.88 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL27647510 0.88 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL28758641 0.88 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL27667922 0.88 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL27647586 0.88 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL811579 0.88 GAA (0.66) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL27667930 0.88 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102834420-B Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP. (US) 2014-10-22 CN claimed
US-8569195-B2 Internal and external donor compounds for olefin polymerization catalysts II BASF CORPORATION (US) 2013-10-29 US claimed
CN-102834420-A Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP 2012-12-19 CN claimed
US-20220127228-A1 METHOD FOR PRODUCING DICHLORO ADDITION PRODUCT OF ALIPHATIC OLEFIN BY PHOTOCATALYSIS UNDER VISIBLE LIGHT SOOCHOW UNIVERSITY (CN) 2022-04-28 US disclosed
WO-2021225823-A1 SYNTHESIS OF VINYLIC PROTECTED ALCOHOL INTERMEDIATES AMGEN INC. (US) 2021-11-11 WO disclosed
CN-105492469-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2018-07-17 CN disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
CN-102834420-B Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP. (US) 2014-10-22 CN disclosed
CN-102834420-A Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP 2012-12-19 CN disclosed
US-8293905-B2 Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-23 US disclosed
US-8088883-B2 Transition metal complex and process for producing conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-03 US disclosed
US-20010051587-A1 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2001-12-13 US disclosed
US-20010031841-A1 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2001-10-18 US disclosed
US-20010029286-A1 Procatalysts, catalyst systems, and use in OLEFIN polymerization EASTMAN CHEMICAL COMPANY, A CORP. OF DELAWARE 2001-10-11 US disclosed
US-20010025005-A1 Procatalysts, catalyst systems, and use in olefin polymerization EASTMAN CHEMICAL COMPANY, A CORPORATION OF DELAWARE 2001-09-27 US disclosed
US-6271321-B1 CATALYTIC POLYMERIZATION OR COPOLYMERIZATION OF ETHYLENE AND OLEFIN MONOMERS EASTMAN CHEMICAL COMPANY 2001-08-07 US disclosed
WO-2001051528-A1 PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION EASTMAN CHEMICAL COMPANY (US) 2001-07-19 WO disclosed
WO-2000075203-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
US-5514642-A HERBICIDES FOR PLANT GROWTH REGULATORS BASF AKTIENGESELLSCHAFT (DE) 1996-05-07 US disclosed
US-4086278-A 1-ALKENYL THIOETHERS ORTHO PHARMACEUTICAL CORPORATION (US) 1978-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127228-A1 METHOD FOR PRODUCING DICHLORO ADDITION PRODUCT OF ALIPHATIC OLEFIN BY PHOTOCATALYSIS UNDER VISIBLE LIGHT AOC1, AOC2, AOC3 ALDH1A1 31/4885TSHR 4420/4885ESR1 1785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.