SCHEMBL197468

SCHEMBL197468

N#Cc1ccc(O)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20646149 0.83 MMP3 (0.57)
SCHEMBL1521420 0.76
SCHEMBL7921018 0.76
SCHEMBL14473167 0.76 CYP19A1 (0.41)
SCHEMBL31172969 0.75 GRM5 (0.54)
SCHEMBL995794 0.75 GRM5 (0.54)
SCHEMBL3778779 0.74
SCHEMBL1026572 0.73 ALDH1A1 (0.48)
SCHEMBL239071 0.71
SCHEMBL221465 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8119563-B2 N-substituted azacycles FMC CORPORATION (US) 2012-02-21 US claimed
US-20090215821-A1 N-Substituted Azacycles FMC CORPORATION 2009-08-27 US claimed
CN-100475791-C Method for preparing 6-hydroxyl-3-cyanogen pyridine SHANDONG INST LIGHT INDUSTRY (CN) 2009-04-08 CN claimed
EP-1673083-A4 N-SUBSTITUTED AZACYCLES BAYER CROPSCIENCE AG (DE) 2008-12-17 EP claimed
CN-101270082-A Method for preparing 6-hydroxyl-3-cyanogen pyridine SHANDONG INST LIGHT INDUSTRY (CN) 2008-09-24 CN claimed
EP-1673083-A2 N-SUBSTITUTED AZACYCLES FMC CORPORATION (US) 2006-06-28 EP claimed
WO-2005036961-A2 N-SUBSTITUTED AZACYCLES FMC CORPORATION (US) 2005-04-28 WO claimed
CN-1526823-A Production process of hydroxylated and coupled microbe with double substrate of nicotinic acid and cyanopyridine ����ʦ����ѧ 2004-09-08 CN claimed
CN-1051803-C Process for producing 6-hydroxy nitrogen-containing six-membered ring compound MITSUBISHI CHEM IND (JP) 2000-04-26 CN claimed
EP-0558022-B1 Process for preparing 3-cyano-6-hydroxypyridine MITSUBISHI CHEM CORP (JP) 1996-06-12 EP claimed
US-5436145-A REACTING 3-CYANOPYRIDINE WITH A MICROORGANISM OR AN EXTRACT THEREOF IN AN AQUEOUS MEDIUM MITSUBISHI KASEI CORPORATION (JP) 1995-07-25 US claimed
US-4209467-A COBALT COMPLEX CATALYST DAICEL LTD. (JP) 1980-06-24 US claimed
US-4043992-A Method for preparing acylated products KYOWA HAKKO KOGYO CO., LTD. (JA) 1977-08-23 US claimed
JP-6197781-A None JP disclosed
JP-8053418-A None JP disclosed
JP-7206821-A None JP disclosed
US-4046896-A 1-Methyl-2-(pyridyl-oxymethyl)-5-nitro-imidazoles HOECHST AKTIENGESELLSCHAFT (DT) 1977-09-06 US disclosed
US-RE29369-E AMIDE PRODUCT, SALTS OF HYDROXY-SUBSTITUTED PYRIDINE COMPOUNDS KYOWA HAKKO KOGYO CO., LTD. (JA) 1977-08-23 US disclosed
US-4043992-A Method for preparing acylated products KYOWA HAKKO KOGYO CO., LTD. (JA) 1977-08-23 US disclosed
US-3963728-A ACYLATION OF NITROGEN CONTAINING COMPOUNDS USING ESTERS KYOWA HAKKO KOGYO CO., LTD. (JA) 1976-06-15 US disclosed