SCHEMBL197473

SCHEMBL197473

O=S(=O)(O)c1cc(Cl)cc(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.46
FYN P06241 1/20 0.46
TSHR P16473 4/20 0.44
ING2 Q9H160 1/20 0.44
FABP4 P15090 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
FBP1 P09467 1/20 0.41
CNR1 P21554 1/20 0.41
TPMT P51580 1/20 0.40
LMNA P02545 1/20 0.40
ALDH1A1 P00352 3/20 0.39
ACP1 P24666 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
FLT1 P17948 2/20 0.39
FLT4 P35916 2/20 0.39
KDR P35968 2/20 0.39
NT5E P21589 1/20 0.39
SOD1 P00441 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4304711 0.97 LCK (0.44) LCKFYNTSHRING2FABP4
Hydrochloric Acid SCHEMBL27989889 0.97 LCK (0.44) LCKFYNTSHRING2FABP4
SCHEMBL11409650 0.94 LCK (0.46) LCKFYNTSHRING2FABP4
SCHEMBL4448090 0.87 ALDH1A1 (0.42) LCKFYNTSHRING2FABP4
SCHEMBL17262670 0.85 LMNA (0.44) LCKFYNTSHRING2FABP4
SCHEMBL8165416 0.84 ALDH1A1 (0.50) LCKFYNTSHRING2SMN1; SMN2
SCHEMBL1510131 0.84 LCK (0.39) LCKFYNTSHRING2FABP4
SCHEMBL4440767 0.82 LCK (0.52) LCKFYNING2FABP4CNR1
1,3,5-Trichlorobenzene SCHEMBL11198172 0.79 TSHR (0.53) TSHRFABP4FBP1TPMTALDH1A1
SCHEMBL18700980 0.79 PGR (0.43) ALDH1A1KMT2AFLT1FLT4KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119060339-A Polyarylene sulfide and preparation method thereof 新凝合科技(成都)有限公司 2024-12-03 CN claimed
CN-114605310-B Synthesis method of aza five-membered ring and three-membered ring carboxylic ester derivative and salt thereof 都创(上海)医药科技股份有限公司 2024-05-07 CN claimed
CN-113683942-B Polyimide water-based epoxy coating and preparation method thereof 成都普利美特科技有限公司 2022-04-29 CN claimed
CN-113683942-A Polyimide water-based epoxy coating and preparation method thereof 成都普利美特科技有限公司 2021-11-23 CN claimed
CN-112694473-A 7, 9-disubstituted berberine derivative and preparation method and application thereof 南京林业大学 2021-04-23 CN claimed
EP-0147867-A2 Method for the enzymatic determination of inorganic phosphate, and its application de Groot, Herbert, Dr. (DE) 1985-07-10 EP claimed
CN-119060339-A Polyarylene sulfide and preparation method thereof 新凝合科技(成都)有限公司 2024-12-03 CN disclosed
CN-117940168-A 2-Amino-4-carboxamide-benzazepine immunoconjugates and uses thereof 博尔特生物治疗药物有限公司 2024-04-26 CN disclosed
CN-116744978-A anti-HER 2 immunoconjugates and uses thereof 博尔特生物治疗药物有限公司 2023-09-12 CN disclosed
CN-112694473-B 7, 9-disubstituted berberine structural analogue and preparation method and application thereof 南京林业大学 2022-09-20 CN disclosed
WO-2022090448-A1 NOVEL ACYLATING REAGENTS NOVO NORDISK A/S (DK) 2022-05-05 WO disclosed
CN-113683942-B Polyimide water-based epoxy coating and preparation method thereof 成都普利美特科技有限公司 2022-04-29 CN disclosed
CN-113683942-B Polyimide water-based epoxy coating and preparation method thereof 成都普利美特科技有限公司 2022-04-29 CN disclosed
EP-0904314-A1 PROCESS FOR PRODUCING SULPHUR-CONTAINING POLYMERS Ticona GmbH (DE) 1999-03-31 EP disclosed
WO-1998022525-A2 METHOD FOR THE PRODUCTION OF SULPHOROUS POLYMERS TICONA GMBH (DE) 1998-05-28 WO disclosed
WO-1997047676-A1 PROCESS FOR PRODUCING SULPHUR-CONTAINING POLYMERS TICONA GMBH (DE) 1997-12-18 WO disclosed
US-5688908-A Process for the preparation of aromatic sulfur-containing polymers HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-18 US disclosed
EP-0798330-A2 Process for preparing aromatic, sulfur containing, polymers HOECHST AKTIENGESELLSCHAFT (DE) 1997-10-01 EP disclosed
EP-0737705-A2 Process for the preparation of sulphur-containing polymers HOECHST AKTIENGESELLSCHAFT (DE) 1996-10-16 EP disclosed
US-4591553-A Process and analytical agent for the determination of the activity of glutamate-oxalacetate-transaminase BOEHRINGER MANNHEIM GMBH (DE) 1986-05-27 US disclosed