SCHEMBL4440767

SCHEMBL4440767

O=C(c1cc(Cl)cc(S(=O)(=O)O)c1)c1cc(Cl)cc(S(=O)(=O)O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.52
FYN P06241 1/20 0.52
TPMT P51580 1/20 0.41
FLT1 P17948 2/20 0.40
FLT4 P35916 2/20 0.40
KDR P35968 2/20 0.40
PGR P06401 1/20 0.40
TTR P02766 1/20 0.38
CNR1 P21554 3/20 0.37
CNR2 P34972 3/20 0.37
ACP1 P24666 1/20 0.37
FABP4 P15090 2/20 0.37
HCAR1 Q9BXC0 1/20 0.36
ING2 Q9H160 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11409650 0.82 LCK (0.46) LCKFYNCNR1FABP4ING2
SCHEMBL197473 0.82 LCK (0.46) LCKFYNTPMTFLT1FLT4
SCHEMBL4304711 0.80 LCK (0.44) LCKFYNTPMTFLT1FLT4
Hydrochloric Acid SCHEMBL27989889 0.80 LCK (0.44) LCKFYNTPMTFLT1FLT4
SCHEMBL4465360 0.77 TPMT (0.65) TPMTTTRCNR1CNR2HCAR1
SCHEMBL4448090 0.76 ALDH1A1 (0.42) LCKFYNCNR1ACP1FABP4
SCHEMBL4452331 0.75 LCK (0.52) LCKFYNACP1ING2CA12
SCHEMBL11349722 0.75 LCK (0.52) LCKFYNING2CA12CA1
SCHEMBL17262670 0.74 LMNA (0.44) LCKFYNFABP4HCAR1ING2
SCHEMBL13522023 0.73 LCK (0.42) LCKFYNFLT1FLT4KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090269645-A1 POLYMER, POLYMER ELECTROLYTE AND FUEL CELL USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-29 US disclosed