Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11051859 | 0.89 | MAOB (0.49) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6865965 | 0.86 | MAOB (0.51) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL14962141 | 0.86 | MAOB (0.50) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6121074 | 0.85 | NPC1 (0.53) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1057908 | 0.84 | MAOB (0.49) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11964039 | 0.83 | ALDH1A1 (0.49) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL31496023 | 0.83 | MAOB (0.53) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL12089304 | 0.83 | MAOB (0.53) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL793834 | 0.82 | ALDH1A1 (0.47) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL29790025 | 0.82 | ALDH1A1 (0.47) | MAOBMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240202-A2 | MODIFIED TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE POLYMERASES | ANSA BIOTECHNOLOGIES, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| EP-4276198-A2 | NUCLEIC ACID SYNTHESIS AND SEQUENCING USING TETHERED NUCLEOSIDE TRIPHOSPHATES | The Regents of The University of California Santa Cruz (US) | 2023-11-15 | — | — | EP | disclosed |
| EP-3825412-B1 | NUCLEIC ACID SYNTHESIS AND SEQUENCING USING TETHERED NUCLEOSIDE TRIPHOSPHATES | UNIV CALIFORNIA (US) | 2023-08-30 | — | — | EP | disclosed |
| US-11732283-B2 | Nucleic acid synthesis and sequencing using tethered nucleoside triphosphates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-08-22 | — | — | US | disclosed |
| WO-2023115047-A2 | COMPOSITIONS FOR ENZYMATIC POLYNUCLEOTIDE SYNTHESIS AND METHODS OF USE | ANSA BIOTECHNOLOGIES, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023115040-A2 | METHODS OF POLYNUCLEOTIDE SYNTHESIS | ANSA BIOTECHNOLOGIES, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| US-11624079-B2 | Polymerase-tethered nucleotides for nucleic acid synthesis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-04-11 | — | — | US | disclosed |
| US-20220205008-A1 | Nucleic Acid Synthesis and Sequencing Using Tethered Nucleoside Triphosphates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-06-30 | — | — | US | disclosed |
| US-11254961-B2 | Polymerase-tethered nucleoside triphosphates for use in nucleic acid synthesis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-02-22 | — | — | US | disclosed |
| EP-3825412-A1 | NUCLEIC ACID SYNTHESIS AND SEQUENCING USING TETHERED NUCLEOSIDE TRIPHOSPHATES | The Regents of The University of California (US) | 2021-05-26 | — | — | EP | disclosed |
| EP-3475450-B1 | NUCLEIC ACID SYNTHESIS AND SEQUENCING USING TETHERED NUCLEOSIDE TRIPHOSPHATES | UNIV CALIFORNIA (US) | 2020-12-09 | — | — | EP | disclosed |
| EP-3475450-A1 | NUCLEIC ACID SYNTHESIS AND SEQUENCING USING TETHERED NUCLEOSIDE TRIPHOSPHATES | The Regents of The University of California (US) | 2019-05-01 | — | — | EP | disclosed |
| US-20190112627-A1 | Nucleic Acid Synthesis and Sequencing Using Tethered Nucleoside Triphosphates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-04-18 | — | — | US | disclosed |
| WO-2017223517-A1 | NUCLEIC ACID SYNTHESIS AND SEQUENCING USING TETHERED NUCLEOSIDE TRIPHOSPHATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11624079-B2 | Polymerase-tethered nucleotides for nucleic acid synthesis | RNGTT, POLN, POLM | MAOB 1577/4885MEN1 3059/4885KMT2A 1288/4885 |
| US-20220205008-A1 | Nucleic Acid Synthesis and Sequencing Using Tethered Nucleoside Triphosphates | RNGTT, DNTT, TYMP | MAOB 1666/4885MEN1 2192/4885KMT2A 985/4885 |
| US-11254961-B2 | Polymerase-tethered nucleoside triphosphates for use in nucleic acid synthesis | RNGTT, POLN, TYMP | MAOB 1480/4885MEN1 2981/4885KMT2A 1194/4885 |
| US-11732283-B2 | Nucleic acid synthesis and sequencing using tethered nucleoside triphosphates | RNGTT, DNTT, TYMP | MAOB 1666/4885MEN1 2192/4885KMT2A 985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.