SCHEMBL19749043

SCHEMBL19749043

C=C1NC(=O)C(C)=CN1C1CC(O)C(CC(C)(C)C)O1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ ALOX12 P18054 1/20 0.32
▸ ADRA1A P35348 1/20 0.32
▸ TK1 P04183 2/20 0.32
▸ TK2 O00142 1/20 0.32
▸ ADRB1 P08588 1/20 0.32
▸ DNMT1 P26358 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13169197 0.87 TK1 (0.43) LMNASMN1; SMN2ALOX12ADRA1ATK1
SCHEMBL15459905 0.73 LMNA (0.48) LMNASMN1; SMN2ALOX12ADRA1ATK1
SCHEMBL16234376 0.73 TK1 (0.48) LMNASMN1; SMN2ALOX12ADRA1ATK1
SCHEMBL17732550 0.73 LMNA (0.48) LMNASMN1; SMN2ALOX12ADRA1ATK1
SCHEMBL17232106 0.72 LMNA (0.35) LMNASMN1; SMN2
SCHEMBL17232090 0.72 TK1 (0.35) TK1
SCHEMBL26941474 0.72 LMNA (0.54) LMNATK1
SCHEMBL16158115 0.72 TK1 (0.36) LMNATK1
SCHEMBL17232091 0.72 LMNA (0.36) LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL13949130 0.72 RNASE1 (0.36) LMNATK1TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11874280-B2 Use of divalent metals for enhancement of fluorescent signals Sony Group Corporation (JP) 2024-01-16 — — US disclosed
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-04-27 — — US disclosed
US-9851359-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups SONY CORPORATION OF AMERICA (US) 2017-12-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 LMNA 201/4885SMN1; SMN2 1247/4885ALOX12 4443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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