Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19756277 | 0.80 | DPP7 (0.36) | USP2TSHR | |
| SCHEMBL15371671 | 0.80 | ALDH1A1 (0.37) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL22390106 | 0.80 | USP2 (0.34) | USP2TSHR | |
| SCHEMBL21536841 | 0.79 | KDM4E (0.33) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL20670283 | 0.77 | KDM4E (0.33) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL20644790 | 0.77 | KDM4E (0.33) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL19756275 | 0.77 | KDM4E (0.33) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL19756273 | 0.77 | KDM4E (0.36) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL19756280 | 0.77 | KDM4E (0.33) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL23959248 | 0.76 | KDM4E (0.33) | ALDH1A1KDM4EPKMDNM1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170368189-A1 | CNP PRODRUGS | ASCENDIS PHARMA GROWTH DISORDERS A/S (DK) | 2017-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170368189-A1 | CNP PRODRUGS | NPPA, NPR1, NPR3 | ALDH1A1 2309/4885KDM4E 2704/4885PKM 2370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.